Evidence map›Paper›PMID 41101508›Full record

Trial reportThe Journal of nutrition2025

Ingestion of 20 g Whey or Canola Protein Does Not Further Increase Muscle Protein Synthesis Rates During Recovery From Resistance Exercise In Healthy, Young Females.

Noortje Boot, Wesley Jh Hermans, Lisa Me Kuin, Julia M Malowany, Floris K Hendriks, Ines Warnke, Joan M Senden, Alex Overman, Joy Pb Goessens, Antoine Zorenc and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05664269 (The Evaluation of Canola Protein and Whey Protein to Support Muscle Conditioning in Vivo in Young Females), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05664269 naunknown statusnot on this map

The Evaluation of Canola Protein and Whey Protein to Support Muscle Conditioning in Vivo in Young Females

TypeinterventionalSponsorMaastricht University Medical CenterRan2023 to 2024Enrolled36ConditionsMuscle Protein SynthesisArmsdrink ingestion, resistance-type exercise
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Noortje BootNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Wesley Jh HermansNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Lisa Me KuinNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Julia M MalowanyNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Floris K HendriksNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Ines Warnkedsm-firmenich, AG, Human Nutrition and Care (HNC) Innovation, R&D and Regulatory, Kaiseraugst, Switzerland.
Joan M SendenNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Alex OvermanNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Joy Pb GoessensNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Antoine ZorencNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Esther KornipsNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Lex B VerdijkNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Luc Jc van LoonNUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands. Electronic address: l.vanloon@maastrichtuniversity.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProtein ingestion during recovery from exercise can further increase muscle protein synthesis rates. Plant-derived proteins are generally believed to have lesser anabolic properties than animal-derived proteins. To our knowledge, no studies have compared the impact of plant-derived with that of animal-derived protein ingestion on postexercise muscle protein synthesis rates in healthy, young females.

objectivesThis study compared muscle protein synthesis rates following the ingestion of 20 g native canola protein, 20 g whey protein, or a noncaloric placebo during recovery from a single bout of resistance exercise in healthy, young females.

methodsIn this randomly assigned, parallel group, double-blind placebo-controlled design, 36 healthy young (age, 23 ± 4 y; BMI, 22.7 ± 2.2 kg/m

resultsPlasma essential amino acid concentrations strongly increased following ingestion of both whey and canola protein when compared with the placebo treatment (peak: 2113 ± 354, 1249 ± 173, and 780 ± 60 μmol/L, respectively; P < 0.001) with greater postprandial plasma essential amino acid availability following whey than after canola protein ingestion (incremental AUC, 158 ± 50 and 90 ± 23 mmol/L × 5 h; P < 0.001). No significant differences in postexercise muscle protein synthesis rates were observed following the ingestion of whey protein isolate, canola protein isolate, and placebo (0.071 ± 0.015, 0.069 ± 0.016, and 0.061 ± 0.013%/h, respectively; treatment; P = 0.200).

conclusionsA single session of resistance exercise strongly increases muscle protein synthesis rates in young females. Ingestion of 20 g whey or native canola protein does not further augment muscle protein synthesis rates during the early stages of postexercise recovery in healthy, young females. This trial was registered at clinicaltrials.gov as NCT05664269.

Indexed as

ExerciseMuscle ProteinsResistance TrainingWhey ProteinsAdultAmino AcidsDouble-Blind MethodFemaleHumansMuscle, SkeletalYoung AdultAmino AcidsMuscle ProteinsWhey Proteinsfemalesfractional synthesis ratemuscle biopsynative plant-based proteinpostexercise recovery

Identifiers

PMID41101508
PMCPMC12799512

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.