Evidence map›Paper›PMID 41101335›Full record

ArticleChemMedChem2025

Monitoring Apoptotic Activity of Silver(I) Metallodrugs Containing Mefenamic Acid and Mitochondriotropic Agents in Artificial Breast Tumor Tissues.

Christina N Banti, Sotiris K Hadjikakou

Abstract read
In one paragraph

Article in ChemMedChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christina N BantiBiological Inorganic Chemistry laboratory, Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece.ORCID https://orcid.org/0000-0001-6727-2711
Sotiris K HadjikakouBiological Inorganic Chemistry laboratory, Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece.ORCID https://orcid.org/0000-0001-9556-6266

Funding

European Social Fund MIS 6004807
6 · The paper itself

Abstract

The anticancer potential of silver(I) metallodrugs incorporating mefenamic acid and mitochondriotropic agents in 3D spheroid models of hormone-dependent breast cancer cells (MCF-7) is investigated within this work. The compounds, previously evaluated in 2D cultures, demonstrated potent antiproliferative activity with IC

Indexed as

Antineoplastic AgentsApoptosisBreast NeoplasmsCoordination ComplexesMefenamic AcidSilverCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorFemaleHumansMCF-7 CellsMolecular StructureSpheroids, CellularStructure-Activity RelationshipAntineoplastic AgentsCoordination ComplexesMefenamic AcidSilver3D cell cultureantiproliferative activityapoptosisbiological inorganic chemistrymefenamic acid

Identifiers

PMID41101335
PMCPMC12677839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.