Evidence map›Paper›PMID 41100265›Full record

ArticleThe American psychologist

An integrated framework for conceptualizing and measuring gender dysphoria: Development and psychometric evaluation of the Multidimensional Gender Dysphoria Measure.

M Paz Galupo, Louis Lindley, Zakary A Clements

Abstract read
In one paragraph

Article in The American psychologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M Paz GalupoBrown School of Social Work, Washington University in St. Louis.ORCID 0000-0002-7991-9970
Louis LindleyDepartment of Counseling Psychology, University of Wisconsin-Madison.
Zakary A ClementsSchool of Education, Loyola University Chicago.

Funding

Gender Dysphoria as a Measure of Proximal Stress: Development and Psychometric Evaluation of a Novel Measure of Social Gender DysphoriaR21MH127529 · NIMH · TOWSON UNIVERSITY · PI GALUPO, PAZ · 2022 to 2023
$411k
National Institutes of Health; National Institute of Mental HealthNIMH NIH HHS R21 MH127529
6 · The paper itself

Abstract

The current article presents an integrated community-informed framework from which to conceptualize the complexity of gender dysphoria and the social context in which it is navigated. Our multidimensional model of gender dysphoria uses a systems-based approach to consider aspects of gender dysphoria that are experienced across individual, interpersonal, structural, and cultural levels. It is from this broad framework that we developed and conducted a psychometric evaluation of the Multidimensional Gender Dysphoria Measure (MGDM). Measure items were developed around five hypothesized subscales with input from content experts and refined through cognitive interviews. The initial 83 items were administered to 599 transgender and nonbinary participants (53.76% people of color) who endorsed diverse gender identities (i.e., 41.1% nonbinary, 24.5% women, and 34.4% men). Exploratory factor analysis revealed a five-factor structure that was upheld during confirmatory factor analysis, representing (a) body gender dysphoria, (b) social gender dysphoria, (c) variability of gender dysphoria, (d) gender dysphoria relief, and (e) internalized gender normativity. The final 25-item scale was found to be invariant across gender, race, and assigned sex, allowing the MGDM to be used to make meaningful within-group comparisons that are not confounded by measurement error. Overall, the MGDM evidenced partial convergent, discriminant, and incremental predictive validity. The MGDM allows for a multidimensional conceptualization of gender dysphoria that is inclusive of both body and social components. Conceptually grounded in both gender normativity and gender minority stress theory, the MGDM can guide further research in these important areas of transgender and nonbinary health. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Indexed as

Gender DysphoriaPsychometricsTransgender PersonsAdolescentAdultFactor Analysis, StatisticalFemaleGender IdentityHumansMaleMiddle AgedReproducibility of ResultsYoung Adult

Identifiers

PMID41100265
PMCPMC12614349

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.