Evidence map›Paper›PMID 41100108›Full record

ArticleJAMA2025

Pathogenic Germline Variants in Cancer Susceptibility Genes.

Gideon Idumah, Daphne Newell, Madeleine Hadrys, Isabella Ribaudo, Ying Ni, Joshua Arbesman

Abstract read
In one paragraph

Article in JAMA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Navigating the healthcare system with aGynecologic oncology reports · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Population-based Characterization of PTEN Hamartoma Tumor Syndrome.medRxiv : the preprint server for health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gideon IdumahCenter for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic Research, Cleveland Clinic, Cleveland, Ohio.
Daphne NewellCleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Madeleine HadrysDepartment of Biology, Case Western Reserve University, Cleveland, Ohio.
Isabella RibaudoDepartment of Dermatology, Cleveland Clinic Medical Specialty Institute, Cleveland, Ohio.
Ying NiCenter for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic Research, Cleveland Clinic, Cleveland, Ohio.
Joshua ArbesmanDepartment of Dermatology, Cleveland Clinic Medical Specialty Institute, Cleveland, Ohio.

Funding

Modeling Autism and Comorbid Cancer Risk in Individuals with Germline PTEN MutationsR01HD105049 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI Ying Ni, Sujata Patil · 2022 to 2026
$1.8M
NICHD NIH HHS R01 HD105049
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41100108
PMCPMC12532028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.