Evidence map›Paper›PMID 41100045›Full record

ArticleBreast cancer (Tokyo, Japan)2026

"Safety and efficacy of early drain removal in breast reconstruction: a retrospective cohort study".

Daiju Goto, Azusa Oshima, Tatsuya Onishi, Takuya Higashino

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Article in Breast cancer (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daiju GotoDepartment of Plastic and Reconstructive Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, Japan. daiju1023goto@gmail.com.ORCID http://orcid.org/0009-0002-8397-8321
Azusa OshimaDepartment of Plastic and Reconstructive Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, Japan.
Tatsuya OnishiDepartment of Breast Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
Takuya HigashinoDepartment of Plastic and Reconstructive Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClosed-suction drains are routinely used in breast reconstruction, but evidence regarding early removal remains limited. This study evaluated whether early drain removal affects local wound complications.

methodsWe retrospectively reviewed patients who underwent breast reconstruction with tissue expanders (TE), implants, or autologous tissue between January 2019 and August 2024. Patients were divided into two groups: a volume-based group (drains removed when output < 30 mL/24 h) and an early-removal group (drains removed within 4 days postoperatively). Incidences of seroma, surgical site infection (SSI), and implant removal within one year postoperatively were compared.

resultsA total of 265 reconstructions in 241 patients were analyzed (134 volume-based, 131 early-removal). Seroma incidence was similar between groups. However, SSI occurred significantly less frequently in the early-removal group than in the volume-based group (21/134 (15.7%) vs. 9/131 (6.9%), p = 0.032). This reduction was evident only in TE/implant-based reconstructions. Multivariable analysis identified early drain removal as an independent protective factor against SSI (OR, 0.316; p = 0.015).

conclusionsEarly drain removal within 4 days does not increase seroma risk and is associated with a significantly lower SSI rate in TE/implant-based breast reconstruction. These findings suggest early drain removal is both safe and beneficial in selected patients.

Indexed as

Breast NeoplasmsDevice RemovalDrainageMammaplastySeromaSurgical Wound InfectionAdultAgedBreast ImplantsFemaleHumansIncidenceMiddle AgedRetrospective StudiesTissue Expansion DevicesBreast reconstructionClosed suction drainDrain removalInfectionSeroma

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.