Evidence map›Paper›PMID 41099990›Full record

ArticleJA clinical reports2025

Pain reduction through combined spinal cord stimulation and exercise therapy after spinal extradural arachnoid cystectomy: a case report.

Akari Ikemura, Daigo Shiroki, Satoshi Ohga, Takafumi Hattori, Yoko Sugiyama, Yuko Kito, Maki Mizogami, Takako Matsubara, Hiroki Iida

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JA clinical reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akari IkemuraAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Daigo ShirokiAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Satoshi OhgaAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Takafumi HattoriAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Yoko SugiyamaAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Yuko KitoAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Maki MizogamiAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Takako MatsubaraAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan.
Hiroki IidaAnesthesiology and Pain Relief Center, Central Japan International Medical Center, 1-1 Kenkounomachi, Minokamo, Gifu, 505-8510, Japan. h-iidamd@xqd.biglobe.ne.jp.ORCID http://orcid.org/0000-0003-0924-598X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinal extradural arachnoid cysts (SEACs) can cause persistent pain after surgery. Combining spinal cord stimulation (SCS) with structured exercise therapy may aid long-term pain modulation. CASE PRESENTATION: A teenage female with over two years of severe rib pain and bilateral leg pain/numbness was diagnosed with SEACs and underwent resection. A trial of SCS alleviated leg symptoms; rib pain persisted. After SCS implantation, leg symptoms resolved, and a gradual exercise progressed from pain-free stretching to low-intensity lower-limb exercises. Over 12 months, rib pain decreased and skeletal muscle mass increased. Pressure pain threshold and conditioned pain modulation improved, suggesting reduced sensitization and enhanced descending inhibition.

conclusionsThis case suggests that SCS may provide early pain relief, enabling initiation of structured exercise, associated with sustained pain reduction, improved pain modulation, and functional recovery. These observations suggest the SCS combined with exercise may be a useful option for selected patients with movement-limiting multifocal pain.

Indexed as

Exercise therapySpinal cord stimulationSpinal extradural arachnoid cysts

Identifiers

PMID41099990
PMCPMC12532969

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