ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2026
Circular over-the-wire pulsed field ablation for atrial fibrillation: differences in outcomes between conscious sedation or general anesthesia.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pulsed field ablation for the interventional treatment of atrial fibrillation: a scientific statement of the European Heart Rhythm Association of the European Society of Cardiology, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, the Latin American Heart Rhythm Society, and the Canadian Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Guideline
- Anaesthetic Techniques for Cardiac Ablation-A Scoping Review.Acta anaesthesiologica Scandinavica · 2026Article
- Pulsed-Field Ablation for Atrial Fibrillation in Partial Anomalous Pulmonary Venous Return With Right Atrial Drainage of Both Right Pulmonary Veins.Journal of arrhythmia · 2026Article
- Controversy: pulsed field ablation is the standard technique for all the candidates for atrial fibrillation ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary vein isolation (PVI) using pulsed field ablation (PFA) is typically performed under general anesthesia (GA) due to patient discomfort and pain. However, procedures under GA require specialized personnel for airway management. PFA systems with suitable characteristics may enable PFA-procedures to be performed under bolus- administered conscious sedation (CS).
objectiveAssess the feasibility, safety, and efficacy of performing PVI with a circular-over-the-wire PFA catheter under CS, compared to GA.
methodsWe conducted a single-center registry study of atrial fibrillation (AF) patients undergoing an ablation with the circular over-the-wire PFA catheter, between January 29 and December 31, 2024, at the St. Antonius Hospital, The Netherlands. CS was used if no anesthesiology team was available. Endpoints included acute isolation of ablation targets, procedural characteristics and freedom from adverse events.
resultsThe analysis included 174 consecutive patients (67.2% male, mean age 62.8 ± 9.3 years), with 62.1% having paroxysmal AF. GA was used in 132 patients (75.9%). There were no differences in baseline characteristics between the groups. Total number of applications was higher in the GA group: 33.0 [IQR 32.0; 36.0] vs. 32.0 [IQR 32.0; 33.0], p < 0.001. Median skin-to-skin procedural time was comparable between groups: GA 39.0 min [IQR 34.0;46.0] vs. CS 42.0 min [IQR 37.5; 46.0], P = N.S. Acute procedural efficacy was 100% in both groups. One patient in the GA group experienced a major bleeding complication.
conclusionConscious sedation offers an efficient and safe alternative to general anesthesia for patients undergoing a procedure with use of the circular over-the-wire PFA catheter.
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