Trial reportTechniques in coloproctology2025
Bilateral posterior tibial nerve stimulation as a neuromodulation strategy for obstructed defecation: a randomized controlled trial.
Trial report in Techniques in coloproctology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObstructed defecation syndrome (ODS) is a prevalent pelvic floor disorder, often impairing patients' quality of life. Noninvasive therapies, including posterior tibial nerve stimulation (PTNS), have been explored as alternative treatments. This study evaluates the efficacy of bilateral transcutaneous posterior tibial nerve stimulation (BT-PTNS) compared to medical treatment alone in patients with ODS without anatomical abnormalities.
methodsA prospective randomized controlled study was conducted on 50 patients diagnosed with ODS. Patients were randomly assigned into two groups: group A received BT-PTNS sessions three times weekly for 6-12 weeks alongside medical treatment, while group B received medical treatment only. Outcomes were assessed using the Modified Obstructed Defecation Syndrome (MODS) score, Patient Assessment of Constipation Quality of Life (PAC-QOL) questionnaire, and quantitative electromyography of pelvic floor muscles. Statistical analysis was performed using SPSS software.
resultsGroup A exhibited a significant reduction in MODS scores (mean decrease = 10 points) compared to group B (mean decrease = 4 points) after 6 weeks (p < 0.001). PAC-QOL scores improved significantly in group A (65% reduction) compared to group B (37% reduction). Electromyographic analysis in group A showed significant improvement in amplitude, number of motor unit turns, and duration (p < 0.001). No adverse events were reported in either group.
conclusionBT-PTNS is a safe and effective noninvasive treatment for ODS without anatomical abnormalities, significantly improving symptom severity and quality of life. Further multicentric trials are warranted to standardize treatment protocols and assess long-term outcomes.
trial registrationClinical Trial Number IORG0008812; E/C.S/N.R2/2017.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.