ReviewNaunyn-Schmiedeberg's archives of pharmacology2026
Sex differences in the response to treatment of attention deficit hyperactivity disorder.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Aniracetam restores the excitation-inhibition balance of neurotransmitters in the prefrontal cortex of mice with ADHD.Scientific reports · 2026Article
- Real-world evaluation of attention deficit hyperactivity disorder symptoms and side effects in patients prescribed serdexmethylphenidate/dexmethylphenidate or other stimulants.Frontiers in pharmacology · 2026Article
- The Effect of ADHD Stimulant Treatment on Weight Categories in Children and Adolescents.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attention deficit hyperactivity disorder (ADHD) impacts markedly on juvenile development and daily function of young and adult patients. Global prevalence and drug prescription rates are consistently on the rise, particularly in young women. Personal experience in daily psychotherapy practice supports sex differences in how the disorder manifests and how the patients respond to treatment. We review sex differences in therapeutic and adverse responses to the cornerstone ADHD pharmacotherapies methylphenodate and amphetamines, under consideration of preclinical mechanistic insights, clinical studies, and relevance for real-life psychotherapy practice. Overall, many gaps in knowledge remain regarding sex differences on all levels of ADHD disease manifestation, diagnosis, and therapy, and the underlying mechanistic basis. Certain treatment strategies may be more or less appropriate, safe, and effective in specific patients, an aspect which warrants further attention in future guideline reforms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.