Evidence map›Paper›PMID 41099824›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Visual outcomes of cataract surgery using multifocal intraocular lenses in young adults with developmental vs. nondevelopmental cataracts.

Fan Yang, Peimin Lin, Ao Miao, Jie Xu, Dongjin Qian, Zihan Xie, Mingyang Wang, Tianyu Zheng

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Fan Yang *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Peimin Lin *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Ao Miao *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Jie XuEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Dongjin QianEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Zihan XieEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Mingyang WangDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China. wangmingyang@shsy11.wecom.work.
Tianyu ZhengDepartment of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China. susu0102@163.com.

Funding

National Natural Science Foundation of China 81300747National Natural Science Foundation of China 82101103Natural Science Foundation of Shanghai 19ZR1408600Natural Science Foundation of Shanghai 22ZR1410400the Excellent Young Doctor Training Program of Shanghai (2015-2018), Shanghai Municipal Health Commission the Excellent Young Doctor Training Program of Shanghai (2015-2018), Shanghai Municipal Health Commissionthe Medicine + X Interdisciplinary Research Project of Tongji University (2025) 2025-0553-YB-07the Scientific Research Program of Shanghai Pudong New Area Health Commission (the Joint Research and Development Program) PW2024D-05Young Clinical Scientist Training Program, funding from Fudan University Shanghai Medical College 2023, DGF828019-2/038
6 · The paper itself

Abstract

purposeTo compare visual outcomes following cataract surgery with multifocal intraocular lenses (MIOLs) in young adult patients with developmental cataracts (DCs) versus nondevelopmental cataracts (NDCs).

methodsIn this retrospective cohort study, patients aged 20–45 years were divided into the DC group (n = 16) and the NDC group (n = 17). The NDC group consisted of patients with high myopic, uveitic, steroid-induced, diabetic and traumatic cataracts caused by injuries in adulthood. Individuals with signs of amblyopia were excluded. At least one month post-surgery, uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), distance-corrected intermediate visual acuity (DCIVA), uncorrected near visual acuity (UNVA), distance-corrected near visual acuity (DCNVA), wavefront aberrations, modulation transfer function (MTF), point spread function (PSF), and contrast sensitivity (CS) were measured. Functional vision was assessed using the Visual Function Index-14 (VF-14) questionnaire.

resultsNo significant differences in UDVA, CDVA, UIVA, DCIVA, DCNVA at 40 cm, UNVA at 33 cm, or DCNVA at 33 cm were observed between the two groups (P > 0.05). However, compared with the NDC group, the DC group had a greater postoperative UNVA at 40 cm (P = 0.04). Overall, the visual quality of the NDC and DC groups was comparable. Compared with the NDC group, the DC group exhibited significantly fewer ocular aberrations and more corneal aberrations but also demonstrated better MTF (HO) values and CS and VF-14 scores (P < 0.05).

conclusionMIOLs can yield favorable visual outcomes for DC patients when strict inclusion criteria are applied.

Indexed as

CataractLens Implantation, IntraocularMultifocal Intraocular LensesPhacoemulsificationPseudophakiaRefraction, OcularVisual AcuityAdultContrast SensitivityFemaleFollow-Up StudiesHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesCataract surgeryDevelopmental cataractMultifocal intraocular lensesVisual acuityVisual quality

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.