Evidence map›Paper›PMID 41099813›Full record

ArticleSkeletal radiology2026

Lumbosacral plexus and sciatic nerve injury following acetabular fracture: predictive value of CT bony features and perineural hematoma.

Keithan Vigna, Andrew Sertic, Larry Robinson, Bin Lin, Thiru Sivakumaran

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Article in Skeletal radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Keithan VignaTemerty School of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Andrew SerticTemerty School of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Larry RobinsonTemerty School of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Bin LinTemerty School of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Thiru SivakumaranTemerty School of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. thirusivakumaran@gmail.com.ORCID http://orcid.org/0000-0003-0659-8325

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSciatic nerve injury is a rare, devastating complication of acetabular fracture. PURPOSE: assess CT predictive value (bony features and perineural hematoma) for sciatic nerve injury following acetabular fracture. MATERIALS AND

methodsIRB-approved retrospective study (n = 471) from 2011 to 2022. Single rater evaluated each case for Judet-Letournel subtype, joint congruence loss, and posterior displacement. Three raters assessed perineural hematoma in zones 1-3: obturator internus, piriformis, and posterior thigh. EMG/NCS confirmed sciatic injury in 20 cases. Sensitivity, specificity, PPV, NPV, OR, and accuracy (AUC) were computed for each marker. Intra- and inter-rater reliability was calculated.

resultsSciatic injury was most frequent in associated both column (8.0%) and transverse family (5.9%) fractures. Sensitivity and specificity of fracture features on sciatic injury were both column involvement (0.85 [17/20], 0.31 [140/451]), congruence loss (0.90 [18/20], 0.36 [163/451]), and posterior displacement (0.70 [14/20], 0.54 [244/451]). Joint congruence loss (OR 5.08, p = 0.016) and posteriorly displaced fragment (OR = 2.74, p = 0.04) were statistically significant (p < 0.05). For hematoma, sensitivity and specificity were zone 1, 0.65-0.80 [13/20-16/20] and 0.30-0.36 [136/451-161/451]; zone 2, 0.60-0.80 [12/20-16/20] and 0.39-0.57 [176/451-255/451]; and zone 3, 0.15-0.25 [3/20-5/20] and 0.69-0.86 [312/451-388/451]. AUC values were zone 1, 0.65-0.71 (satisfactory-to-good); zone 2, 0.69-0.71; and zone 3, 0.48-0.61 (poor-to-satisfactory). Values were significant in zones 1 and 2. Intra-rater reliability (Gwet's AC2) was almost perfect in zone 1 (0.86-0.87), moderate to almost perfect in zones 2-3 (0.47-0.90). Inter-rater agreement (Gwet's AC2) in zones 1-3 was 0.73 (substantial), 0.49 (moderate), and 0.50.

conclusionWe found three statistically significant predictors of sciatic nerve injury following acetabular fracture: joint congruence loss, posteriorly displaced bone fragment, and perineural hematoma at the level of (a) obturator internus and (b) piriformis. Rater agreement for perineural hematoma was excellent for zone 1.

Indexed as

AcetabulumFractures, BoneHematomaLumbosacral PlexusPeripheral Nerve InjuriesSciatic NerveSciatic NeuropathyTomography, X-Ray ComputedAdolescentAdultAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsAcetabular fractureLumbosacral plexus injurySciatic nerve injury

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.