ArticleMicrobial ecology2025
Endophytic bacterial diversity of Vicatia thibetica collected from Xizang and the association with flavonoid accumulation.
Article in Microbial ecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Vicatia thibetica de Boiss is a unique medicinal and edible plant endemic to Xizang, China. It is one of the five primary root medicines in Tibetan medicine due to its high content of flavonoids. However, the community composition of endophytic bacteria in its various tissues and their potential role in flavonoid accumulation remain unclear. We employed high-throughput sequencing to compare the diversity of endophytic bacteria in the rhizosphere soil and various tissues of V. thibetica collected from three sampling sites in Nyingchi, Xizang. Concurrently, we assessed the types and concentrations of flavonoids present in the roots. Finally, we investigated the relationship between root endophytic bacteria and flavonoid accumulation through correlation analysis. The results indicated that the diversity and abundance of bacterial communities in the rhizosphere soil exceeded those of the endophytic bacterial communities of V. thibetica. Proteobacteria is the dominant phylum, and Sphingomonas is the dominant genus. Each tissue of a plant exhibits its dominant genus. PICRUSt predictive analysis revealed that RNA processing and modification were the predominant functions among related species. Targeted metabolomics analysis has revealed that the roots of the plants contain 14 flavonoid compounds. Correlation analysis revealed that the concentrations of flavonoids in the roots, including apigenin, rutin, astragalin, quercetin 3-glucoside, L-epicatechin, kaempferol, and luteolin, are associated with the distribution and abundance of specific bacterial genera, such as Lactobacillus, Kurthia, Bradyrhizobium, Phenylobacterium, Novosphingobium, and Mycobacterium, among others. This finding suggests that these bacterial genera may directly influence the production and accumulation of flavonoids in the plant. Our findings will enhance the understanding of plant-microbe interactions and provide crucial insights into the role of endophytes in the production of V. thibetica and its significant secondary metabolites.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.