ArticlePediatric radiology2026
Diagnostic performance of ultrasound guided salivary gland core needle biopsy and fine needle aspiration in children.
Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundUltrasound-guided biopsies of the salivary glands in pediatric patients are uncommon and can target focal lesions or general parenchyma. Based on open surgical biopsy, 65% of focal lesions have been described as benign. Ultrasound-guided biopsy offers a less invasive initial diagnostic approach.
objectiveThe aims of this study were to assess the diagnostic accuracy and describe indications for ultrasound-guided salivary gland core needle biopsy (CNB) and fine needle aspiration (FNA) in a pediatric cohort. MATERIALS AND
methodsRetrospective single-center study including children who underwent salivary gland biopsy at a tertiary care center from January 2018 to January 2025. Demographics, clinical information, imaging, lesion location, procedure details, adverse events, pathology, and clinical outcomes were reviewed. A descriptive statistical analysis was performed.
resultsThe study included 31 children aged 5 months to 17-years-old. The parotid was targeted in 21/31 (68%) and the submandibular in 10/31 (32%). CNB was done in 19/31 patients, 11/31 had a CNB and FNA, and 1/31 FNA only. CNB was diagnostic in 29/30 and FNA in 8/12. When both techniques were used, pathological findings were the same in 7/11. The most common diagnosis was pleomorphic adenoma (n=6). All CNB in cases of malignancy (n=10) were diagnostic. The non-diagnostic case identified was a dermoid cyst in surgery. Nine patients had surgical resections, and the results were consistent with the ultrasound-guided biopsy. No adverse events were identified.
conclusionUltrasound-guided CNB showed a high diagnostic performance, superior to FNA, in this salivary gland biopsies pediatric cohort.
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