Evidence map›Paper›PMID 41099635›Full record

ArticleACS applied materials & interfaces2025

Monitoring Response to Combinatorial Immunotherapies by Tracking both T Cells and Natural Killer Cells

Gabriel P Cutshaw, Siddhant Kothadiya, Saji Uthaman, Darpan N Pandya, Xiaona Wen, Ansuja Mathew, Akesh Sinha, Irine Antony, Anna E Vilgelm, Thaddeus J Wadas and 2 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gabriel P CutshawDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0003-0474-0631
Siddhant KothadiyaDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.ORCID 0009-0009-5782-6448
Saji UthamanDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0001-6387-7510
Darpan N PandyaDepartment of Radiology, University of Iowa, Iowa City, Iowa 52242, United States.
Xiaona WenNanovaccine Institute, Iowa State University, Ames, Iowa 50012, United States.ORCID 0000-0003-0441-4393
Ansuja MathewDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.
Akesh SinhaDepartment of Radiology, University of Iowa, Iowa City, Iowa 52242, United States.
Irine AntonyDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.
Anna E VilgelmDepartment of Pathology, The Ohio State University, Columbus, Ohio 43210, United States.
Thaddeus J WadasDepartment of Radiology, University of Iowa, Iowa City, Iowa 52242, United States.ORCID 0000-0002-9913-0336
Jason S MitchellCenter for Immunology, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Rizia BardhanDepartment of Chemical and Biological Engineering, Iowa State University, Ames, Iowa 50011, United States.ORCID 0000-0002-5854-652X

Funding

Combining senescence-inducing and senolytic agents to improve melanoma therapyR37CA233770 · NCI · VANDERBILT UNIVERSITY · PI VILGELM, ANNA E · 2019 to 2025
$2.4M
Developing Multimodal Multiplexed ImmunoPET-Raman Probes to Guide ImmunotherapiesR01EB029756 · NIBIB · IOWA STATE UNIVERSITY · PI BARDHAN, RIZIA · 2020 to 2024
$1.2M
NCI NIH HHS R37 CA233770NIBIB NIH HHS R01 EB029756
6 · The paper itself

Abstract

Real-time imaging of multiple immunomarkers

Indexed as

CD8-Positive T-LymphocytesGoldImmunotherapyKiller Cells, NaturalMetal NanoparticlesPositron-Emission TomographyAnimalsCell Line, TumorCopper RadioisotopesFemaleHumansMiceSpectrum Analysis, RamanTumor MicroenvironmentCopper RadioisotopesGoldgold nanoparticlegold nanostarimmunoPETimmunotherapymultiplexingsurface-enhanced Raman spectroscopy

Identifiers

PMID41099635
PMCPMC12581125

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.