Evidence map›Paper›PMID 41099091›Full record

ArticleAddiction (Abingdon, England)2025

High potency cannabis flower use is associated with heavier consumption and risk for cannabis use disorder among young adults in California, United States.

Michael S Dunbar, Elizabeth J D'Amico, Rachana Seelam, Jordan P Davis, Eric R Pedersen, Anthony Rodriguez, Beau Kilmer

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Observational
  3. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael S DunbarDepartment of Behavioral and Policy Sciences, RAND Corporation, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0002-2644-0413
Elizabeth J D'AmicoDepartment of Behavioral and Policy Sciences, RAND Corporation, Santa Monica, CA, USA.ORCID https://orcid.org/0000-0002-8527-7804
Rachana SeelamDepartment of Behavioral and Policy Sciences, RAND Corporation, Santa Monica, CA, USA.
Jordan P DavisDepartment of Behavioral and Policy Sciences, RAND Corporation, Santa Monica, CA, USA.
Eric R PedersenDepartment of Behavioral and Policy Sciences, RAND Corporation, Santa Monica, CA, USA.
Anthony RodriguezDepartment of Behavioral and Policy Sciences, RAND Corporation, Boston, MA, USA.
Beau KilmerDepartment of Behavioral and Policy Sciences, RAND Corporation, Santa Monica, CA, USA.ORCID https://orcid.org/0000-0002-9333-8080

Funding

Brief Voluntary Alcohol and Drug Intervention for Middle School YouthR01AA016577 · NIAAA · RAND CORPORATION · PI D'AMICO, ELIZABETH J. · 2007 to 2011
$4.5M
Psychometric Evaluation of AHIMSA ScaleR01AA025848 · NIAAA · RAND CORPORATION · PI D'AMICO, ELIZABETH J. · 2017 to 2021
$3.7M
Adolescent AOD Use Trajectories: The Role of Race and EthnicityR01AA020883 · NIAAA · RAND CORPORATION · PI D'AMICO, ELIZABETH J. · 2012 to 2016
$3.5M
Life Course Perspective on Alcohol and Drug Use Trajectories from Adolescence into AdulthoodR01AA028812 · NIAAA · RAND CORPORATION · PI D'AMICO, ELIZABETH J. · 2021 to 2025
$3.1M
NIAAA NIH HHS R01 AA016577NIAAA NIH HHS R01AA016577NIAAA NIH HHS R01 AA020883NIAAA NIH HHS R01AA020883NIAAA NIH HHS R01 AA025848NIAAA NIH HHS R01AA025848NIAAA NIH HHS R01 AA028812NIAAA NIH HHS R01AA028812
6 · The paper itself

Abstract

aimsTo measure associations between frequency and quantity consumed of cannabis flower for different levels of delta-9-tetrahydrocannabinol (THC) concentration.

designCross-sectional survey.

settingCalifornia, USA (survey fielded June 2022-July 2023).

participantsYoung adults (n = 512) with mean age 25.86 (standard deviation = 0.87) years, 48.04% female, from a California-based cohort study, who endorsed past-month cannabis flower use. MEASUREMENTS: Individuals completed survey items on cannabis use behavior (e.g. past-month use frequency, quantity consumed), symptoms of cannabis use disorder [using the Cannabis Use Disorder Identification Test - Revised (CUDIT-R)] and self-reported knowledge and perceived THC content (potency) of typical flower used. Multivariable linear and logistic regression models examined associations between perceived flower potency [rated on a scale from No THC (0) to Very High THC (5)], use behavior and CUDIT-R scores, adjusting for sociodemographic characteristics.

findingsNearly one in five respondents (18.55%) indicated that they did not know the THC potency of flower typically used. Among those who endorsed knowing potency, nearly half (46.76%) endorsed typically using High or Very High THC flower. Results from separate adjusted linear regression models showed that a one-point increase in the perceived THC potency scale was associated with 3.33 more use days per month [B = 3.33, (standard error, SE = 0.46), P < 0.0001], 0.13 more grams of flower used per day [B = 0.13 (SE = 0.04), P < 0.01] and 1.21 greater CUDIT-R scores [B = 1.21 (SE = 0.29), P < 0.0001].

conclusionsSelf-reported use of higher potency cannabis flower appears to be associated with more frequent and higher-quantity cannabis consumption and greater Cannabis Use Disorder Identification Test - Revised (CUDIT-R) scores, which is inconsistent with the notion that individuals titrate use of higher-potency cannabis.

Indexed as

CannabisDronabinolFlowersMarijuana AbuseMarijuana UseAdultCaliforniaCross-Sectional StudiesFemaleHumansMaleYoung AdultDronabinolcannabiscannabis use disorderdrug use behaviorpotencysmokingTHCyoung adults

Identifiers

PMID41099091
PMCPMC12614250

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.