Evidence map›Paper›PMID 41099004›Full record

ReviewAnnals of cardiothoracic surgery2025

From back table innovation to contemporary application: a review of the frozen elephant trunk technique.

Gabriel Weiss, Zsuzsanna Arnold, Sandra Folkmann, Thomas Aschacher, Sebastian Tauber, Marie-Luise Harrer, Bernhard Winkler, Jennifer Stabernak, Michael Gorlitzer, Martin Grabenwöger

Abstract readReview
In one paragraph

Review in Annals of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriel WeissDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Zsuzsanna ArnoldDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Sandra FolkmannDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Thomas AschacherDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Sebastian TauberDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Marie-Luise HarrerDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Bernhard WinklerDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Jennifer StabernakDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Michael GorlitzerDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.
Martin GrabenwögerDepartment of Cardiovascular Surgery, Clinic Floridsdorf, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The frozen elephant trunk (FET) technique represents a significant advancement in the surgical management of complex aortic pathologies involving the aortic arch and descending thoracic aorta. This review traces the evolution of the FET procedure from its conceptual origins in the conventional elephant trunk (ET) technique to its current application as a hybrid, single-stage intervention. The FET technique integrates open surgical repair with endovascular technology, allowing for simultaneous aortic arch replacement and stent-graft deployment into the descending aorta. Key indications include acute and chronic aortic dissections, arch aneurysms, and malperfusion syndromes. Surgical considerations such as cannulation strategy, cerebral protection, and spinal cord preservation are discussed in detail, with emphasis on techniques that enhance safety and outcomes. The development of commercially available FET prostheses-such as E-vita Open Neo, Thoraflex Hybrid, and Frozenix-has improved procedural versatility and enabled individualized treatment strategies. Innovations in graft design, including proximalization of distal anastomosis and integration of side branches, have further simplified the procedure and broadened its applicability. Despite variability in outcomes across patient populations, the FET procedure is associated with favorable early and mid-term results, including reduced inter-stage mortality and enhanced aortic remodeling. The technique continues to evolve, driven by advances in device technology and a growing emphasis on tailored, patient-specific surgical approaches.

Indexed as

aortic arch replacementFrozen elephant trunk (FET)hybrid aortic surgery

Identifiers

PMID41099004
PMCPMC12519270

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.