Evidence map›Paper›PMID 41098879›Full record

ReviewClinical, cosmetic and investigational dermatology2025

Inflamed Skin, Burdened Heart: A Multidisciplinary Perspective on Atopic Dermatitis and Cardiovascular Health.

Chenghui Ma, Yikang Xu, Wenshuo Bai, Yulin Zou

Abstract readReview
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chenghui Ma *Department of Geriatrics, The Fourth People's Hospital of Shenyang, Shenyang, Liaoning, 110031, People's Republic of China.
Yikang Xu *Department of Cardiovascular Medicine, The Second Affiliated Hospital of Shenyang Medical College, Shenyang, 110002, People's Republic of China.
Wenshuo BaiDepartment of Cardiology, Jinzhou Central Hospital, Jinzhou, Liaoning, 121000, People's Republic of China.
Yulin ZouDepartment of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.ORCID 0000-0001-5747-3720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diseases of both skin and cardiovascular are the most significant global medical challenges for their high rates of morbidity and mortality. Although not life-threatening, skin diseases significantly impair patients' quality of life and affect a large proportion of the population due to their chronic and persistent nature. Cardiovascular diseases are characterized by both a widespread prevalence and a high risk of mortality, posing a significant public health burden. As both skin diseases and cardiovascular diseases fall under the umbrella of inflammatory disorders, a degree of pathophysiological connection exists between them. Historically, the potential interplay between these seemingly unrelated conditions was largely overlooked. However, accumulating evidence in recent years has suggested that inflammatory skin diseases-particularly Atopic Dermatitis (AD)-may be associated with an elevated risk of adverse cardiovascular outcomes. This review therefore not only examines the emerging interdisciplinary links between AD and cardiology, but also highlights ongoing controversies, the limitations of current evidence, and outlines future research directions needed to clarify their shared inflammatory pathways and clinical implications.

Indexed as

atopic dermatitiscardiovascularheartinflammationskin

Identifiers

PMID41098879
PMCPMC12519999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.