Evidence map›Paper›PMID 41098780›Full record

ArticleFrontiers in nutrition2025

Association of lifestyle, dietary pattern, and liver function with cognition in older adults: findings from a cross-sectional study.

Xixiang Wang, Xiuwen Ren, Yu Liu, Lu Liu, Jingjing Xu, Shaobo Zhou, Ying Wang, Linhong Yuan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xixiang WangSchool of Public Health, Capital Medical University, Beijing Key Laboratory of Environment and Aging, China-British Joint Laboratory of Nutrition Prevention and Control of Chronic Diseases, Beijing, China.
Xiuwen RenSchool of Public Health, Capital Medical University, Beijing Key Laboratory of Environment and Aging, China-British Joint Laboratory of Nutrition Prevention and Control of Chronic Diseases, Beijing, China.
Yu LiuSchool of Public Health, Capital Medical University, Beijing Key Laboratory of Environment and Aging, China-British Joint Laboratory of Nutrition Prevention and Control of Chronic Diseases, Beijing, China.
Lu LiuSchool of Public Health, Capital Medical University, Beijing Key Laboratory of Environment and Aging, China-British Joint Laboratory of Nutrition Prevention and Control of Chronic Diseases, Beijing, China.
Jingjing XuSchool of Public Health, Capital Medical University, Beijing Key Laboratory of Environment and Aging, China-British Joint Laboratory of Nutrition Prevention and Control of Chronic Diseases, Beijing, China.
Shaobo ZhouSchool of Science, Faculty of Engineering and Science, University of Greenwich, Chatham, United Kingdom.
Ying WangSuzhou Research Center of Medical School, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou, China.
Linhong YuanSchool of Public Health, Capital Medical University, Beijing Key Laboratory of Environment and Aging, China-British Joint Laboratory of Nutrition Prevention and Control of Chronic Diseases, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Single lifestyle, dietary pattern, and liver function are closely associated with cognitive ability, yet their combined influences on cognition remain unclear. This study aimed to investigate the effects of lifestyle, dietary patterns, and liver function on cognitive impairment among older adults. Methods: One thousand and ninety-six older adults were recruited from communities. Among them, 630 participants completed cognitive function tests. The lifestyle and dietary patterns of the participants were assessed using a healthy lifestyle score (HLS) and a healthy dietary score (HDS). Liver function was assessed using four predictive indicators: AST/HDL-C, ALT/HDL-C, HSI, and ZJU. Cognitive function was measured using the Montreal Cognitive Assessment (MoCA). Logistic regression, receiver operating characteristic curves (ROC), and restricted cubic splines (RCS) were applied to explore the relationship between variables. Results: A significant negative correlation was observed between HLS and liver function indicators ( Conclusion: Impaired liver function is strongly associated with cognitive impairment, highlighting the critical role of maintaining healthy liver function in preventing MCI in the elderly. A healthy lifestyle positively correlated with both liver and cognitive functions, and a balanced diet significantly improved cognitive outcomes.

Indexed as

AST/HDL-Cdietary patternlifestyleliver functionmild cognitive impairment

Identifiers

PMID41098780
PMCPMC12518086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.