ArticleFrontiers in oncology2025
Rare renal tumor: a case report of juxtaglomerular cell tumor and literature review.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Rapidly progressive giant renin secreting tumor: a rare case report.Urology case reports · 2026Article
- Malignant reninoma with pulmonary metastasis and ATRX mutation treated with olaparib: a case report of specialized treatment.Frontiers in immunology · 2026Article
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9 authors.
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Abstract
Juxtaglomerular Cell Tumor (JGCT) is an extremely rare neoplasm of the kidney that poses a significant clinical challenge in terms of accurate diagnosis. The key to successful treatment lies in the accurate identification of renal lesion. Excessive secretion of renin by JGCT causes activation of renin-angiotensin-aldosterone system (RAAS) secondary to uncontrollable hypertension, hypokalemia and consequently a range of clinical manifestations. While most JGCTs are benign, there have been reports of malignant cases, thus requiring close follow-up. In this case report, the subject is a middle-aged female patient who has suffered from recurrent poorly controlled blood pressure for a number of years. Following a medical examination, the patient was found to have the right renal mass, which was pathologically confirmed to be JGCT after laparoscopic partial right nephrectomy. Thereafter, the patient's blood pressure recovered steadily during the subsequent follow-up period. Furthermore, a comprehensive summary of the diagnosis, differential diagnosis, treatment and review of case reports of JGCT from the last decade is provided, encompassing malignant biological behaviors.
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