Evidence map›Paper›PMID 41098605›Full record

ArticleSpine surgery and related research2025

Skeletal Maturity, Brace Compliance, and In-Brace Correction Rate Are Important Factors Associated with Cobb Angle Progression after Brace Treatment in Patients with Adolescent Idiopathic Scoliosis.

Kotaro Sakashita, Tomoyuki Asada, Toshiaki Kotani, Tsuyoshi Sakuma, Yasushi Iijima, Yosuke Ogata, Shun Okuwaki, Shuhei Ohyama, Masaya Mizutani, Tsutomu Akazawa and 4 more

Abstract read
In one paragraph

Article in Spine surgery and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Would initial thoracic correction be a key factor in orthotic intervention for adolescent idiopathic scoliosis with double-curve?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kotaro SakashitaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Tomoyuki AsadaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Toshiaki KotaniDepartment of Orthopedic Surgery, Seirei Sakura Citizen Hospital, Sakura, Japan.
Tsuyoshi SakumaDepartment of Orthopedic Surgery, Seirei Sakura Citizen Hospital, Sakura, Japan.
Yasushi IijimaDepartment of Orthopedic Surgery, Seirei Sakura Citizen Hospital, Sakura, Japan.
Yosuke OgataDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Shun OkuwakiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Shuhei OhyamaDepartment of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Masaya MizutaniDepartment of Orthopedic Surgery, Seirei Sakura Citizen Hospital, Sakura, Japan.
Tsutomu AkazawaDepartment of Orthopedic Surgery, St. Marianna University School of Medicine, Kawasaki, Japan.
Shohei MinamiDepartment of Orthopedic Surgery, Seirei Sakura Citizen Hospital, Sakura, Japan.
Seiji OhtoriDepartment of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Masao KodaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.
Masashi YamazakiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, Tsukuba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study investigated brace treatment for patients with adolescent idiopathic scoliosis (AIS) to comprehensively evaluate the factors associated with curve progression, including the effects of in-brace correction rate (ICR) and objective brace compliance. Additionally, it aimed to establish a clinically useful optimal ICR threshold for effective curve progression control. Methods: In this single-center retrospective analysis of prospectively collected data, 116 patients with AIS, with Cobb angles of 20°-40° and at least 1-year follow-up were included. Patients whose Cobb angles progressed by >5° were classified into the progressed group, whereas the others were categorized into the non-progressed group. Bracing time was objectively assessed using a thermometer. Results: In this study, 19 (16.4%) patients were assigned to the progressed group. Open triradiate cartilage was significantly more frequent in the progressed group (22.2% vs. 2.6%, p=0.011) whereas no significant differences were observed in demographics or pre-brace Cobb angles. The progressed group demonstrated a lower ICR (26.8% vs. 39.5%, p=0.002) and shorter bracing time at 6 months (14.0 hours vs. 17.4 hours, p=0.042). Multivariate logistic regression analysis revealed that Sanders grade (1-4), ICR, and bracing time were independently associated with Cobb angle progression (odds ratios: 7.01, 0.95, and 0.89, respectively; all p<0.05). Based on receiver operating characteristic curve analysis, the ICR threshold of 38.3% was identified to achieve a clinically significant negative predictive value of 95%. Conclusions: Under objective bracing time monitoring, skeletal maturity, ICR, and bracing time were crucial factors in preventing curve progression 1 year after brace initiation in patients with Cobb angles of 20°-40°. An ICR of 38.3% is recommended as the target when bracing adjustments are feasible.

Indexed as

adolescent idiopathic scoliosisbrace compliancebrace treatmentin-brace correction rateskeletal maturity

Identifiers

PMID41098605
PMCPMC12519109

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.