Evidence map›Paper›PMID 41098398›Full record

ArticleNutrition research and practice2025

Effects of vitamin D supplementation on T cell activation and regulatory T cell development in

Yunjung Lee, Dalli Nam, Soomin Yoo, Woo Young Choi, YuJing Lu, Ga Young Lee, Hyewon Shin, Sung Nim Han

Abstract read
In one paragraph

Article in Nutrition research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunjung LeeDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0006-7379-6996
Dalli NamDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0008-9810-1809
Soomin YooDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0002-8519-9831
Woo Young ChoiDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0003-5746-3647
YuJing LuDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0000-3531-1667
Ga Young LeeDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0000-0002-3906-0671
Hyewon ShinDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0009-0009-8836-7942
Sung Nim HanDepartment of Food and Nutrition, College of Human Ecology, Seoul National University, Seoul 08826, Korea.ORCID https://orcid.org/0000-0003-0647-2992

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesAtherosclerosis is a chronic inflammatory disease characterized by the buildup of low-density lipoprotein (LDL) within arterial walls, triggering inflammation and vascular constriction. Vitamin D has been shown to suppress T cell proliferation, reduce inflammatory responses, and promote the development of regulatory T cells (Tregs). However, its role in modulating T cell function in atherosclerotic models is not fully understood. This study examined the effects of vitamin D supplementation on T cell activation and Treg development in MATERIALS/

methodsC57BL/6J mice (CON) were fed a control diet (10% kcal fat), while B6.129S7-

resultsThe expression of TCR signaling genes (

conclusionThe higher

Indexed as

Atherosclerosishypoxiaregulatory T cellT-cell antigen receptorvitamin D

Identifiers

PMID41098398
PMCPMC12518743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.