SynthesisFrontiers in neurology2025
Efficacy of injection therapies in reducing hemiplegic shoulder pain: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Objective: This systematic review of randomized controlled trials (RCTs) with meta-analysis aimed to investigate the efficacy of injection therapies in reducing hemiplegic shoulder pain (HSP) in stroke survivors. Methods: PubMed, Embase and the Cochrane databases were searched from inception to April 20, 2025 to identify RCTs of stroke survivors with HSP undergoing injection therapies to reduce pain intensity. The main outcome of the assessment was the degree of pain relief as measured by visual analogue scale (VAS). And the secondary outcome indicator is the range of motion (ROM) at the end of the follow-up period. Results: A total of 408 results were identified by the search strategy, and 11 studies were included in the final analysis. We analyzed data for 353 stroke survivors with HSP, the results showed improvement of VAS within 4 weeks after injection was MD -1.03, 95% CI [-1.72, -0.33], Conclusion: This systematic review and meta-analysis indicated that the addition of injection therapies to conventional rehabilitation is more effective than conventional rehabilitation alone in the complex treatment of patients with HSP in terms of both the short-term and long-term follow-up. Systematic review registration: The protocol for this systematic review and meta-analysis was prospectively registered with PROSPERO (CRD420251040988).
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