Evidence map›Paper›PMID 41098345›Full record

ArticleChina CDC weekly2025

Active Surveillance on Safety and Compliance of Freeze-dried Human Rabies Vaccine (Vero Cell) - Jiangsu Province, China, 2023-2024.

Yanjun Chen, Mingwei Wei, Xiaoteng Xu, Yunfeng Shi, Shixuan Zhang, Chenhao Wang, Qi Liang, Xue Guo, Hongxing Pan

Abstract read
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanjun Chen *Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing City, Jiangsu Province, China.
Mingwei Wei *Jiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing City, Jiangsu Province, China.
Xiaoteng XuChangchun Institute of Biological Products Co., Ltd., Changchun City, Jilin Province, China.
Yunfeng ShiJiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing City, Jiangsu Province, China.
Shixuan ZhangChangchun Institute of Biological Products Co., Ltd., Changchun City, Jilin Province, China.
Chenhao WangChangchun Institute of Biological Products Co., Ltd., Changchun City, Jilin Province, China.
Qi LiangJiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing City, Jiangsu Province, China.
Xue GuoChangchun Institute of Biological Products Co., Ltd., Changchun City, Jilin Province, China.
Hongxing PanJiangsu Provincial Center for Disease Control and Prevention (Jiangsu Provincial Academy of Preventive Medicine), Nanjing City, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: Both the 4-dose (Zagreb) and 5-dose (Essen) rabies vaccination regimens demonstrate comparable immunogenicity and safety profiles in clinical trials and are approved for use in China. What is added by this report?: This study pioneers active safety surveillance via a mobile application, identifying an adverse reaction rate of 2.10% for the Zagreb regimen and 2.70% for the Essen regimen. The Zagreb regimen had a lower out-of-window administration rate of 8.41% compared to 16.38%. Compliance was influenced by age, marital status, and exposure level, while the Essen regimen involved additional factors, including education level and perceived convenience. What are the implications for public health practice?: This study supports broader adoption of the 4-dose regimen to reduce logistical challenges and enhance compliance. Mobile application-based active surveillance presents a novel approach to enhancing real-world monitoring quality.

Indexed as

active surveillancecompliancerabies vaccinesafety

Identifiers

PMID41098345
PMCPMC12518962

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.