ArticleCureus2025
Association of Vitamin D Deficiency With Glycemic Control in Type 2 Diabetes Mellitus.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Vitamin D is widely acknowledged for its important role in sugar metabolism by influencing inflammatory control, insulin production, and sensitivity. One of the main causes of problems in individuals with type 2 diabetes mellitus (T2DM) is inadequate glycemic management. This study aimed to evaluate the association between glycemic management and vitamin D levels in individuals with T2DM. Methods A total of 200 adult T2DM patients participated in this cross-sectional observational study at the endocrinology department in a tertiary care hospital as outpatients. The participants were divided into two subcategories based on blood glucose control: with a good HbA1c (<7%; n = 76) and with a poor HbA1c (≥7%; n = 124). To measure the levels of serum 25-hydrovitamin D (25(OH)D), a chemiluminescence immunoassay was utilized. 25(OH)D < 20 ng/mL was the indication for vitamin D insufficiency. BMI, gender, age, diabetes duration, and medication schedule were among the demographic and clinical data collected. The statistical analysis employed the chi-square test, the independent t-test, and the Pearson correlation. Statistical significance was defined at p-value <0.05. Results Vitamin D deficiency was present in 145 (72.5%) participants, and 101 (81.5%) individuals demonstrated poor glucose management compared to 44 (57.9%) participants in the good control group (p < 0.001). Patients with poorly controlled diabetes had substantially lower mean 25(OH)D levels (15.8 ± 5.9 ng/mL) than those with well-controlled diabetes (22.1 ± 6.3 ng/mL; p < 0.001). There was a negative correlation (r = -0.45; p < 0.001) between vitamin D levels and HbA1c. Conclusion In patients with T2DM, inadequate glycemic management is associated with vitamin D insufficiency. The findings suggest that, in the context of comprehensive diabetes care, monitoring and adjusting vitamin D levels are beneficial.
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