Bilateral Thalamic Infarction Due to Artery of Percheron Occlusion in a Young Patient With Hyperhomocysteinemia and Vertebral Artery Dissection.

Norma Zuñiga Rivera, Carlos Ricardo Vazquez Sotelo, Andres Reyes Valdes, Alejandra Albarrán Sánchez

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In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Norma Zuñiga RiveraInternal Medicine, Hospital of Specialties, XXI Century National Medical Center, Mexican Institute of Social Security, Mexico City, MEX.

Carlos Ricardo Vazquez SoteloInternal Medicine, Hospital of Specialties, XXI Century National Medical Center, Mexican Institute of Social Security, Mexico City, MEX.

Andres Reyes ValdesInternal Medicine, Hospital of Specialties, XXI Century National Medical Center, Mexican Institute of Social Security, Mexico City, MEX.

Alejandra Albarrán SánchezInternal Medicine, Hospital of Specialties, XXI Century National Medical Center, Mexican Institute of Social Security, Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The artery of Percheron (AOP) is a rare anatomical variant supplying the bilateral paramedian thalami and the rostral midbrain. Its occlusion represents a diagnostic challenge due to the variability in clinical presentation. We report the case of a 20-year-old male who was admitted with altered consciousness and nonspecific neurological symptoms. Magnetic resonance imaging (MRI) demonstrated a characteristic bilateral thalamic infarction consistent with AOP occlusion. Etiological workup revealed hyperhomocysteinemia and a right vertebral artery dissection, the latter suspected to be secondary to chiropractic cervical manipulation. Despite medical treatment and rehabilitation, the patient experienced significant cognitive and motor sequelae. This case highlights the importance of clinical suspicion and prompt diagnosis of AOP occlusion in young patients with atypical cerebrovascular events, emphasizing the need for a comprehensive evaluation to optimize management and improve prognosis.

Indexed as

artery of percheron infarctbilateral thalamic infarctionhyperhomocysteinemia (hhcy)stroke in young populationtraumatic vertebral artery dissection

Identifiers

PMID41098275

DOI10.7759/cureus.92282

PMCPMC12520159

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