Evidence map›Paper›PMID 41098161›Full record

ArticleFree neuropathology2025

ACOX1 gain-of-function post-mortem neuropathology is distinct from ACOX1 loss-of-function: case report and literature review.

Zita Hubler, Kaleigh Filisa Roberts, Nima Sharifai, Julia Sim, Sophia A Hung, Grace E Robvais, Alan Pestronk, Robert E Schmidt, Sonika Dahiya, Robert C Bucelli

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Free neuropathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zita HublerWashington University in St. Louis, Department of Pathology and Immunology, USA.
Kaleigh Filisa RobertsWashington University in St. Louis, Department of Pathology and Immunology, USA.
Nima SharifaiUniversity of Maryland, School of Medicine, Department of Pathology, USA.
Julia SimWashington University in St. Louis, Department of Neurology, USA.
Sophia A HungWashington University in St. Louis, Department of Biology, USA.
Grace E RobvaisWashington University in St. Louis, Department of Biology, USA.
Alan PestronkWashington University in St. Louis, Department of Neurology, USA.
Robert E SchmidtWashington University in St. Louis, Department of Pathology and Immunology, USA.
Sonika DahiyaWashington University in St. Louis, Department of Pathology and Immunology, USA.
Robert C BucelliWashington University in St. Louis, Department of Neurology, USA.

Funding

PREDOCTORAL TRAINING PROGRAM IN MOLECULAR THERAPEUTICST32GM008803 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI MIEYAL, JOHN J, NIEMAN, MARVIN THOMAS · 2001 to 2023
$4.2M
Postdoctoral Training Program in Genomic MedicineT32GM139799 · NIGMS · WASHINGTON UNIVERSITY · PI DICKSON, PATRICIA I · 2021 to 2025
$817k
NIGMS NIH HHS T32 GM008803NIGMS NIH HHS T32 GM139799
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ACOX1Case reportMitchell SyndromePseudo-neonatal adrenoleukodystrophy

Identifiers

PMID41098161
PMCPMC12519239

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.