Evidence map›Paper›PMID 41098144›Full record

ArticleJournal of cosmetic dermatology2025

Optimization of Enzymatic Extraction Process for Peony lactiflora Seed and Its Application in Skin Care.

Zhixiong Chen, Ping Cao, Yong Yang, Yaolin Wen, Shaohui Xia, Guangxi Fan, Jie Zhu

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhixiong ChenHuzhou Jiaheng Industrial Co. Ltd., Huzhou, China.ORCID https://orcid.org/0000-0001-5036-8629
Ping CaoHuzhou Jiaheng Industrial Co. Ltd., Huzhou, China.
Yong YangCollege of Landscape Architecture, Beijing Forestry University, Beijing, China.
Yaolin WenCatch Bio-Science & Technology Co. Ltd., Beijing, China.
Shaohui XiaHuzhou Jiaheng Industrial Co. Ltd., Huzhou, China.
Guangxi FanAnimal Husbandry and Veterinary Station of Wuzhong District, Changsha, China.
Jie ZhuHuzhou Jiaheng Industrial Co. Ltd., Huzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe peony, as a botanical marvel, boasts a wealth of polysaccharides, total flavonoids, paeoniflorin, and other bioactive chemical constituents across all its parts. While past research has primarily concentrated on the flowers and roots of this plant, there has been a relative paucity of investigation into the seeds of Paeoniflora. This paper aimed to bridge this gap by providing a foundational study on the Paeoniflora seeds, offering valuable insights for future research endeavors in this area.

objective(a) Optimization of peony seed extraction process; and (b) exploring the skin beautifying effects of Paeonia lactiflora seed extracts.

methodsOne-way optimization and response surface optimization techniques were used for enzymatic extraction of peony seed extract using DPPH free radical scavenging rate as an evaluation index. Tyrosinase activity inhibition and hyaluronidase inhibition were determined in vitro under optimal extraction conditions.

resultsThe results showed that the maximum DPPH radical scavenging rate of 86.94% ± 1.02% was obtained experimentally under the simulated optimal conditions of 60°C, 0.010 (g/g) solid-liquid ratio, 3.9% (g/g) addition of complex enzyme, 0.39 (g/g) cellulose ratio, and 2.7 h enzymatic hydrolysis time. Meanwhile, the inhibition rate of tyrosinase activity and hyaluronidase inhibition rate were determined under the optimal extraction conditions. The results showed that the inhibition rate of tyrosinase was 61.4% and that of hyaluronidase was 77.7% in the concentration range of 0.5%-2.5%.

conclusionsThe complex enzymatic method is an effective method for the production of peony seed extract with significant antioxidant properties, whitening activity, and soothing effect.

Indexed as

Free Radical ScavengersPaeoniaPlant ExtractsSeedsSkin CareCellulaseHyaluronoglucosaminidaseHydrolysisMonophenol MonooxygenasePolygalacturonaseSkinCellulaseFree Radical ScavengersHyaluronoglucosaminidaseMonophenol MonooxygenasePlant ExtractsPolygalacturonaseDPPHpeony seedresponse surface methodologysoothing effectwater enzymatic methodwhitening

Identifiers

PMID41098144
PMCPMC12529242

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.