Evidence map›Paper›PMID 41098017›Full record

ArticleGlobal health action2025

Bibliometric and visual analysis of global research on endocrine-disrupting chemicals and children's health: evidence, emerging concerns, and research gaps.

Liyan Luo, Jun Guan, Shaohe Hei, Yuxin Liu, Chuyan Wu, Feng Jiang, Jiahui He

Abstract read
In one paragraph

Article in Global health action, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liyan LuoDepartment of Neonatology, Dali Bai Autonomous Prefecture Maternal and Child Health Care Hospital, Dali, China.
Jun GuanDepartment of Gynecology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Shaohe HeiDepartment of Science and Education, Dali Bai Autonomous Prefecture Maternal and Child Health Care Hospital, Dali, China.
Yuxin LiuDiagnostics and Therapeutics of Intractable Diseases, Intractable Disease Research Center, Graduate School of Medicine, Juntendo University, Tokyo, Japan.ORCID 0009-0005-0495-6944
Chuyan WuDepartment of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.ORCID 0000-0002-5622-6020
Feng JiangDepartment of Neonatology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.ORCID 0000-0002-3525-8752
Jiahui HeDepartment of Neonatology, Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.ORCID 0009-0002-7780-3162

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndocrine-disrupting chemicals (EDCs) are environmental pollutants that interfere with hormonal systems and may pose serious risks to children's health during critical developmental stages. Despite many studies, a comprehensive overview of global research trends is still lacking.

objectiveThis study aimed to provide a comprehensive bibliometric and visual analysis of global research trends on EDCs and pediatric health over the past two decades.

methodsRelevant publications from 1 January 2005 to 4 June 2025 were retrieved from the Web of Science Core Collection. Microsoft Excel, CiteSpace, VOSviewer, and the R package 'bibliometrix' were used to analyze publication trends, influential countries, institutions, authorship, journal distribution, keyword co-occurrence, and emerging research topics.

resultsA total of 3,241 publications from 95 countries and regions were identified. The United States led with 38.29% of publications and the highest citation frequency. Among the top 10 productive authors, seven were based in the US. The Centers for Disease Control and Prevention (CDC) was the most prolific institution. Environmental Research published the largest number of articles (199, 6.14%). Major research hotspots included autism spectrum disorder, precocious puberty, child behavior, postnatal exposure, and human exposure. The most frequent keywords were 'endocrine-disrupting chemicals,' 'bisphenol A,' and 'exposure.'

conclusionsThis study provides the first systematic bibliometric overview of global research on EDCs and children's health. The results highlight increasing academic attention and identify key contributors and emerging themes, offering guidance for future research and policy development in pediatric environmental health.

Indexed as

BibliometricsChild HealthEndocrine DisruptorsEnvironmental PollutantsChildEnvironmental ExposureEvidence GapsGlobal HealthHumansEndocrine DisruptorsEnvironmental PollutantsBibliometricpediatric environmental healthprenatal exposurepublic health policyWeb of Science

Identifiers

PMID41098017
PMCPMC12532360

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.