ArticleAnnals of medicine2025
Effect of erector spinae plane block on overall benefit of analgesia after esophagectomy: a randomized controlled trial protocol.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionManagement of postoperative pain following esophagectomy is challenging. This study aims to investigate the analgesic efficacy and overall clinical benefit of erector spinae plane block (ESPB) using either liposomal bupivacaine or ropivacaine in patients undergoing esophagectomy. PATIENTS AND
methodsThis single-center, randomized, double-blind, placebo-controlled trial will be conducted at the First Affiliated Hospital of Soochow University. Eighty-four adult patients scheduled for transthoracic esophagectomy will be randomized (1:1:1) to receive a preoperative ultrasound-guided ESPB using either liposomal bupivacaine, ropivacaine, or normal saline placebo. All patients will receive standardized general anesthesia and postoperative patient-controlled intravenous analgesia with sufentanil. The primary outcome is the mean Overall Benefit of Analgesia Score (OBAS) over postoperative days 1 to 5, a multidimensional tool integrating pain, opioid-related side effects, and patient satisfaction. Secondary outcomes include the OBAS on each of the first 5 postoperative days, cumulative opioid consumption during postoperative 5 days, incidence of major in-hospital complications, length of postoperative hospital stay, and 5-year overall survival. DISCUSSION: Utilizing the OBAS to comprehensively assess analgesic benefit, the findings of this trial will guide evidence-based refinement of multimodal analgesia for patients undergoing esophagectomy.
trial registrationChinese Clinical Trial Registry (ChiCTR2500099481; registered on March 25, 2025).
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