Evidence map›Paper›PMID 41097802›Full record

ReviewCancers2025

The Genomic Topography of Appendiceal Cancers: Our Current Understanding, Clinical Perspectives, and Future Directions.

Daniel J Gironda, Richard A Erali, Steven D Forsythe, Ashok K Pullikuth, Rui Zheng-Pywell, Kathleen A Cummins, Shay Soker, Xianyong Gui, Edward A Levine, Konstantinos I Votanopoulos and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Daniel J GirondaDepartment of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0003-0362-4890
Richard A EraliWake Forest Organoid Research Center, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.ORCID 0000-0002-4649-0450
Steven D ForsytheWake Forest Organoid Research Center, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.ORCID 0000-0003-4099-6642
Ashok K PullikuthDepartment of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0002-0041-3310
Rui Zheng-PywellDepartment of Surgery, Section of Surgical Oncology, Atrium Health Wake Forest Baptist, Winston-Salem, NC 27157, USA.ORCID 0000-0003-4681-8054
Kathleen A CumminsDepartment of Surgery, Section of Surgical Oncology, Atrium Health Wake Forest Baptist, Winston-Salem, NC 27157, USA.
Shay SokerWake Forest Organoid Research Center, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.
Xianyong GuiAtrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC 27157, USA.
Edward A LevineWake Forest Organoid Research Center, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.ORCID 0000-0002-7683-9502
Konstantinos I VotanopoulosWake Forest Organoid Research Center, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.
Lance D MillerDepartment of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0003-3799-2528

Funding

Tumor Organoid-Mediated Drug Testing and Clonality Analysis in Peritoneal Surface Disease of Intestinal OriginR01CA249087 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, LANCE DAVID, VOTANOPOULOS, KONSTANTINOS · 2021 to 2025
$2.5M
Establishing the Repertoire of Actionable Alterations in Appendiceal AdenocarcinomaR01CA258692 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Lance David Miller, Konstantinos Votanopoulos · 2022 to 2026
$2.5M
NCI NIH HHS R01 CA249087NCI NIH HHS R01 CA258692
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

appendix cancerbowel malignancycolon cancermolecular profilingmutational landscapenext-generation sequencingprecision medicine

Identifiers

PMID41097802
PMCPMC12524201

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.