Evidence map›Paper›PMID 41097782›Full record

ReviewCancers2025

MYCN-Driven Metabolic Networks Are a Critical Dependency of High-Risk Neuroblastomas.

Michelle G Pitts, Lindsay T Bryant, Michael D Buoncristiani, Eric J Rellinger

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michelle G PittsDepartment of Surgery, University of Kentucky, Lexington, KY 40536, USA.ORCID 0000-0002-6698-3199
Lindsay T BryantDepartment of Surgery, University of Kentucky, Lexington, KY 40536, USA.
Michael D BuoncristianiDepartment of Surgery, University of Kentucky, Lexington, KY 40536, USA.ORCID 0000-0002-3369-8463
Eric J RellingerDepartment of Surgery, University of Kentucky, Lexington, KY 40536, USA.

Funding

University of Kentucky Center for Cancer MetabolismP20GM121327 · NIGMS · UNIVERSITY OF KENTUCKY · PI Binhua P Zhou · 2017 to 2026
$25.0M
NIGMS NIH HHS P20 GM121327NIH HHS 1P20GM121327-22V Foundation for Cancer Research V2023-026
6 · The paper itself

Abstract

Neuroblastoma is a devastating pediatric solid tumor that, despite significant recent advances, still accounts for nearly 15% of all childhood cancer deaths. Patients are risk stratified based on a number of features, including amplification of the

Indexed as

fatty acidsfucosylationglycolysisglycosylationmetabolismMYCNneuroblastomapolyaminessialic acid

Identifiers

PMID41097782
PMCPMC12523912

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.