Evidence map›Paper›PMID 41097713›Full record

ArticleCancers2025

A Novel Early Memory-Enriched Allogeneic NKG2D CAR-T Cell Therapy Based on CRISPR/Cas9 Technology for Solid Tumors.

Cristina Aparicio, Mónica Queipo, Marina Belver, Francisco Espeso, Julia Serna-Pérez, Lucía Enríquez-Rodríguez, Carlos Acebal, Álvaro Martín-Muñoz, Antonio Valeri, Alejandra Leivas and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Cristina AparicioUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.ORCID 0000-0002-8692-6482
Mónica QueipoUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.
Marina BelverUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.
Francisco EspesoUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.
Julia Serna-PérezUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.
Lucía Enríquez-RodríguezUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.ORCID 0000-0002-9072-5245
Carlos AcebalUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.ORCID 0009-0008-4920-0261
Álvaro Martín-MuñozUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.ORCID 0000-0002-6329-2827
Antonio ValeriHospital Universitario 12 de Octubre-Centro Nacional de Investigaciones Oncológicas (H12O-CNIO) Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, 28029 Madrid, Spain.
Alejandra LeivasHospital Universitario 12 de Octubre-Centro Nacional de Investigaciones Oncológicas (H12O-CNIO) Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, 28029 Madrid, Spain.
Paula RíoBiomedical Innovation Unit, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), 28040 Madrid, Spain.
Daniel J PowellDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104-4238, USA.ORCID 0000-0002-5966-8908
Rosa Lobo-ValentínClinical Genetics Laboratory, Río Hortega University Hospital, 47012 Valladolid, Spain.
David ArrabalClinical Genetics Laboratory, Río Hortega University Hospital, 47012 Valladolid, Spain.
Joaquín Martínez-LópezHospital Universitario 12 de Octubre-Centro Nacional de Investigaciones Oncológicas (H12O-CNIO) Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, 28029 Madrid, Spain.ORCID 0000-0001-7908-0063
Ana SánchezUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.
Miguel Á de la FuenteUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.ORCID 0000-0003-4619-8756
Margarita González-VallinasUnit of Excellence Institute of Biomedicine and Molecular Genetics of Valladolid (IBGM), Higher Council for Scientific Research (CSIC)-University of Valladolid (UVA), 47003 Valladolid, Spain.ORCID 0000-0003-4968-6675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

allogeneiccancer immunotherapychimeric antigen receptor (CAR)CRISPRinterleukinsNKG2Doff the shelfsolid tumorsT-cell memoryT cells

Identifiers

PMID41097713
PMCPMC12523248

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.