Evidence map›Paper›PMID 41097692›Full record

ArticleCancers2025

M2 Macrophage Polarization Mediated by Complement C3 from Hedgehog-Activated Fibroblasts Establishes an Immunosuppressive Niche in Gastric Cancer.

Jiaheng Lou, Jingcheng Zhang, Zhiyuan Song, Shuo Zhang, Sicheng Zhao, Yunhai Wei, Guiping Chen, Tao Jiang, Guangji Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaheng LouSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Jingcheng ZhangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Zhiyuan SongSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Shuo ZhangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID 0009-0005-1096-7148
Sicheng ZhaoSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Yunhai WeiHuzhou Central Hospital, Huzhou 313000, China.
Guiping ChenZhejiang Provincial Hospital of Chinese Medicine, Hangzhou 310006, China.
Tao JiangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Guangji ZhangSchool of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Funding

Key project of the National Nature Foundation of China No. 82030119National Natural Science Foundation of China No. 82204950the Key Support Project of Regional Innovation and Development Joint Fund of National Natural Science Foundation of China U23A20499Zhejiang Chinese Medicine University Chunyan Special Fund for the development of traditional Chinese medicine No. CY202302Zhejiang Provincial Natural Science Foundation of China No. LQ23H270013
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

fibroblastgastric cancerhedgehog signaling pathwaymacrophagesingle-cell RNA-seqT celltumor immunosuppressive microenvironment

Identifiers

PMID41097692
PMCPMC12523485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.