Evidence map›Paper›PMID 41097645›Full record

ReviewCancers2025

Hybrid Angio-CT with DICI-CT in Interventional Oncology and Beyond: A Narrative Review.

Michael Moche, Arjen Bogaards, Andreas Horst Mahnken, Philipp Paprottka, Jonathan Nadjiri, Maciej Pech, Thierry de Baere, Bruno Calazans Odisio

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael MocheDepartment of Interventional Radiology, Heart Center & Helios Park-Hospital, 04289 Leipzig, Germany.
Arjen BogaardsSiemens Healthineers, 91301 Forchheim, Germany.
Andreas Horst MahnkenDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, St. Josef Hospital, Ruhr University Hospital Bochum, 44791 Bochum, Germany.ORCID 0000-0001-8077-9306
Philipp PaprottkaDepartment of Interventional Radiology Clinic Rechts der Isar, Technical University Munich, 80333 Munich, Germany.
Jonathan NadjiriDepartment of Interventional Radiology Clinic Rechts der Isar, Technical University Munich, 80333 Munich, Germany.
Maciej PechDepartment of Radiology and Nuclear Medicine, University Clinic Magdeburg, 39112 Magdeburg, Germany.ORCID 0000-0002-7140-6775
Thierry de BaereDepartment of Interventional Radiology, Gustave Roussy, 94800 Villejuif, France.ORCID 0000-0002-4556-7663
Bruno Calazans OdisioDepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0002-1771-8233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesHybrid Angio-CT suites have emerged in response to the growing demands for innovation and procedural complexity in minimally invasive therapies. It is hypothesized that enhanced image guidance capabilities enabled by multimodality imaging can improve procedural safety, accuracy, and efficacy. However, due to the current lack of sufficient data to support a systematic review, the objective of this article is to present a comprehensive synthesis of the existing literature through a narrative review.

methodsThis narrative review is based on purposefully identified research reports, their critical evaluation, and synthesis by a group of experienced users. The analysis covers three key areas: (1) current state of available technologies and functionalities, (2) novel perspectives through 'Direct Intravascular Contrast media Injection CT' (DICI-CT), and (3) the role of Angio-CT in established and emerging image-guided procedures.

resultsThe review presents typical configurations and room layouts for Angio-CT systems and discusses further technological improvement potential. Selected literature is complemented by expert experience to report on the current state of the art and demonstrate its use and efficiency. Based on our expert experience, it is demonstrated how DICI-CT can be used to reduce contrast dose and improve lesion visualization, targeting, and endpoint determination. Furthermore, in this review the advantages, including survival benefit (i.e., in trans-arterial chemoembolization and in blunt trauma) and cost-effectiveness (i.e., in emergency care), are reviewed with reference to oncologic and non-oncologic applications in both elective and emergency medicine.

conclusionsHybrid Angio-CT suites can provide significant additional imaging information with the potential to improve image-guided procedures. This perspective is increasingly supported by retrospective data in interventional oncology and beyond. Provided that further technological advancements are achieved and prospective clinical data substantiates the anticipated clinical and economical benefits, hybrid Angio-CT suites are anticipated to play a key role in the multimodality interventional suite of the future.

Indexed as

acute careAngio-CThybridImage-guidanceinterventional oncologyintra-arterial CTmulti-modality minimally invasive

Identifiers

PMID41097645
PMCPMC12523905

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.