Evidence map›Paper›PMID 41097630›Full record

ArticleCancers2025

Cancer Burden Attributable to Potentially Modifiable Risk Factors in Australia.

Tenaw Tiruye, Bereket Duko, Laychiluh Mekonnen, Paul Ward, Trang H H D Nguyen, Stephanie Byrne, David Roder, Kerri Beckmann

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Global, regional, and national burden and quality of care index of five head and neck cancers: a 32-year longitudinal analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tenaw TiruyeCancer Epidemiology and Population Health Research Group, Allied Health and Human Performance, University of South Australia, Adelaide 5000, Australia.
Bereket DukoResearch Centre for Public Health, Equity and Human Flourishing (PHEHF), Torrens University Australia, Wakefield Street Campus, Adelaide 5000, Australia.ORCID 0000-0002-4419-0016
Laychiluh MekonnenClinical and Health Sciences, University of South Australia, Adelaide 5000, Australia.ORCID 0000-0001-7108-5345
Paul WardResearch Centre for Public Health, Equity and Human Flourishing (PHEHF), Torrens University Australia, Wakefield Street Campus, Adelaide 5000, Australia.ORCID 0000-0002-5559-9714
Trang H H D NguyenCancer Epidemiology and Population Health Research Group, Allied Health and Human Performance, University of South Australia, Adelaide 5000, Australia.ORCID 0000-0002-8124-6437
Stephanie ByrneSchool of Public Health, University of Adelaide, Adelaide 5005, Australia.ORCID 0000-0001-5566-3467
David RoderCancer Epidemiology and Population Health Research Group, Allied Health and Human Performance, University of South Australia, Adelaide 5000, Australia.
Kerri BeckmannCancer Epidemiology and Population Health Research Group, Allied Health and Human Performance, University of South Australia, Adelaide 5000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the relative contribution of modifiable risk factors to cancer morbidity and mortality is crucial for designing effective cancer prevention and control strategies. Our study estimated cancer-related deaths and disability-adjusted life years (DALYs) lost attributable to potentially modifiable risk factors in Australia using data from the Global Burden of Diseases 2021 study. In 2021, an estimated 20,409 cancer deaths (37.5%) and 431,575 cancer DALYs lost (37.9%) in Australia were attributable to potentially modifiable risk factors. Males had higher modifiable risk attributed to cancer death and DALY rates than females. Behavioral risks accounted for 25.0% of cancer deaths and 26.5% of DALYs. Metabolic risks and environmental/occupational risks accounted for 9.4% and 9.3% of deaths, respectively. Smoking remained the leading attributable risk factor, accounting for 12.2% cancer deaths and 13.1% DALYs lost. Dietary risks accounted for 40.0% of colorectal cancer deaths and DALYs lost. Cervical, larynx, liver, lung, and colorectal cancers had a high proportion of deaths and DALYs lost attributed to modifiable risks. Liver and nasopharyngeal cancers had the highest burden attributed to alcohol use (39.1% and 39.0%, respectively), while 21.3% liver cancer deaths were attributed to drug use. Strengthening public health interventions, such as multi-disciplinary approaches to promote a healthy lifestyle, is required.

Indexed as

Australiadeathdisability-adjusted life yearsglobal burden of diseaseneoplasms

Identifiers

PMID41097630
PMCPMC12524207

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.