Evidence map›Paper›PMID 41097623›Full record

ArticleCancers2025

Single-Fraction SBRT for Locally Advanced Pancreatic Cancer Using Total Intravenous Anaesthesia and Optical Surface Guidance: Technique and Preliminary Results.

Hrvoje Kaučić, Maja Karaman Ilić, Domagoj Kosmina, Ana Mišir Krpan, Sunčana Divošević, Asmir Avdičević, Hrvoje Feljan, Matea Lekić, Karla Schwarz, Dragan Schwarz

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hrvoje KaučićSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.ORCID 0000-0002-9451-1762
Maja Karaman IlićSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.
Domagoj KosminaSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.ORCID 0000-0002-4099-9002
Ana Mišir KrpanSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.
Sunčana DivoševićSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.ORCID 0009-0007-5232-4145
Asmir AvdičevićSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.ORCID 0000-0002-0619-1587
Hrvoje FeljanSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.
Matea LekićSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.
Karla SchwarzSchool of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-9278-660X
Dragan SchwarzSpecialty Hospital Radiochirurgia Zagreb, 10431 Sveta Nedelja, Croatia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this retrospective, single-arm study was to present the technique and preliminary efficacy and safety results of a single-fraction SBRT for LAPC using total intravenous anaesthesia and optical surface guidance as motion management.

methodsFifty-five patients with locally advanced pancreatic cancer were treated with SBRT with a single-fraction receiving a median BED

resultsThe median follow-up was 15 months, mean OS was 18 months (95% CI: 16.7 to 19.3), and the one-year FFLP and 1-year OS were 100% and 90.9% (95% CI: ± 1.5%), respectively. Median PFS was 12 months (95% CI: 9.5 to 14.4), and 1-year PFS was 85.5% (95% CI: ± 1.4%). Thirty-five patients (63.6%) were alive at the time of analysis. No acute/late toxicity > G2/G1 was reported.

conclusionsSBRT for LAPC using total intravenous anaesthesia and optical surface guidance presented as an effective and safe treatment with very low toxicity.

Indexed as

locally advanced pancreatic cancerstereotactic ablative radiotherapystereotactic body radiotherapytotal intravenous anaesthesiatumour motion management

Identifiers

PMID41097623
PMCPMC12523422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.