Evidence map›Paper›PMID 41097580›Full record

ReviewFoods (Basel, Switzerland)2025

A Review of Nutrition, Bioactivities, and Health Benefits of Custard Apple (

Ningli Qi, Xiao Gong, Yang Luo, Chenghan Zhang, Jingjing Chen, Tinghui Chen

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ningli QiSanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya 572019, China.
Xiao GongSanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya 572019, China.ORCID 0000-0003-3709-6926
Yang LuoCollege of Notoginseng Medicine and Pharmacy, Wenshan University, Wenshan 663099, China.
Chenghan ZhangCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Jingjing ChenSanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya 572019, China.
Tinghui ChenAgricultural Products Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524001, China.

Funding

National Natural Science Foundation of China 32360608National Natural Science Foundation of China 32360609Project of Hainan Province Science and Technology Special Fund ZDYF2023XDNY031
6 · The paper itself

Abstract

The custard apple (CA) is a noble fruit in tropical regions worldwide. It has attracted a growing interest due to its organoleptic properties and nutritional value. With the expansion of international trade, both its cultivation and consumption have grown significantly in recent years. Previous researchers have sporadically investigated its nutritional composition and health benefits; however, existing information on its processing and utilization is highly fragmented and lacks a comprehensive overview of its constituents, biological activities, and potential applications. This review is a detailed summary of the nutritional and bioactive properties, safety evaluations, and potential applications of CA. Following PRISMA guidelines, peer-reviewed studies published between 2000 and 2025 were systematically searched in PubMed, Scopus, ResearchGate, and Web of Science. Inclusion criteria comprised studies reporting on nutritional composition, phytochemicals, bioactivities, health promotion, and applications of CA. In addition to primary nutrients like carbohydrates, protein, fatty acids, vitamins, and minerals, CA also contains a multitude of bioactive compounds, mainly including phenols, flavonoids, terpenoids, acetogenins, and alkaloids, which are attributed to a range of health benefits, such as antioxidant, anti-microbial, anti-tumor, blood sugar regulation, and cognitive function improvement. However, more clinical and toxicological profiles remain underexplored, and future research should focus on standardized extraction, safety evaluation, and translational applications. Additionally, the challenges and future perspectives in industrial applications are discussed, which are expected to offer comprehensive information for the utilization of CA.

Indexed as

Annona squamosaapplications progresshealth-promotingnutritional compositionphytochemicals

Identifiers

PMID41097580
PMCPMC12523297

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.