Evidence map›Paper›PMID 41097515›Full record

ArticleFoods (Basel, Switzerland)2025

Flavonoid-Rich Extracts from Lemon and Orange By-Products: Microencapsulation and Application in Functional Cookies.

Giovanna Dellapina, Giovanna Poli, Vanna Moscatelli, Daniela Magalhães, Ana A Vilas-Boas, Manuela Pintado

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giovanna DellapinaExperimental Station for the Food Preserving Industry, Area of Transversal and Multidisciplinary Services-Consumer Science Division, Viale Tanara 31/a, I-43121 Parma, Italy.ORCID 0009-0009-5403-7830
Giovanna PoliExperimental Station for the Food Preserving Industry, Area of Transversal and Multidisciplinary Services-Consumer Science Division, Viale Tanara 31/a, I-43121 Parma, Italy.
Vanna MoscatelliExperimental Station for the Food Preserving Industry, Area of Transversal and Multidisciplinary Services-Consumer Science Division, Viale Tanara 31/a, I-43121 Parma, Italy.
Daniela MagalhãesCBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.ORCID 0000-0001-9728-1635
Ana A Vilas-BoasCBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.ORCID 0000-0002-9051-8123
Manuela PintadoCBQF-Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.ORCID 0000-0002-0760-3184

Funding

Fundação para a Ciência e Tecnologia PRIMA/0014/2019
6 · The paper itself

Abstract

Citrus by-products are increasingly recognized as a valuable source of bioactive compounds (BCs), particularly flavonoids. Their incorporation into food matrices as functional ingredients aligns with sustainability goals and consumer demand for health-promoting products. However, challenges such as poor stability and undesirable sensory properties limit their direct use in food systems. This study aimed to develop and evaluate functional cookies enriched with microencapsulated flavonoid-rich extracts derived from lemon and orange peels. Flavonoids were extracted with hydroethanolic solvent and characterized by HPLC-DAD. The extracts exhibited high total flavonoid contents: 1960.1 mg/L for orange and 845.7 mg/L for lemon. The extracts were encapsulated using a 1% sodium alginate and 1.36% corn starch blend, producing thermally stable microbeads with flavonoid retention higher than 85% after heating at 230 °C for 30 min. These microbeads were incorporated into gluten-free oat and buckwheat cookies, delivering 166.11 mg/100 g (orange) and 177.13 mg/100 g (lemon) of flavonoids in the product, which covers approximately one-third of the recommended daily intake. Sensory analysis using triangle tests (ISO 4120) (n = 23) showed no significant difference (

Indexed as

circular economyfunctional bakery productsmicroencapsulationpolyphenolssensory analysisupcycled ingredient

Identifiers

PMID41097515
PMCPMC12523308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.