Evidence map›Paper›PMID 41097500›Full record

ArticleFoods (Basel, Switzerland)2025

Ultrasound-Assisted Green Natural Deep Eutectic Solvent Extraction of Flavonoids from Wild Blueberry: Process Optimization, Composition Identification, and Antioxidant Activity.

Le Ouyang, Weiwei Liang, Chun Bian, Yi Shan, Shumei Wang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Green Extraction of Phenolic Compounds from Blueberry (Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Enzyme-Assisted Ultrasonic Extraction of Flavonoids fromAntioxidants (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Le OuyangCollege of Food Engineering, Harbin University, Harbin 150086, China.
Weiwei LiangCollege of Food Engineering, Harbin University, Harbin 150086, China.ORCID 0000-0003-1249-8769
Chun BianCollege of Food Engineering, Harbin University, Harbin 150086, China.
Yi ShanCollege of Food Engineering, Harbin University, Harbin 150086, China.
Shumei WangCollege of Food Engineering, Harbin University, Harbin 150086, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To improve the deep processing and utilization of wild blueberries, this study presents a green and highly efficient method for extracting flavonoids from blueberries. The approach combines natural deep eutectic solvents (NADESs) with ultrasound-assisted extraction. Among the 22 tested NADES, Betaine/urea (BU), was the most effective solvent for extracting flavonoids from blueberries. The extraction parameters of ultrasound-assisted betaine/urea (UABU) were optimized using a response surface methodology (RSM). This optimization procedure yielded the optimized conditions outlined below: a molar ratio of urea to betaine of 3.3:1, a water content of 60% (

Indexed as

antioxidant activitycomponent analysisnatural deep eutectic solventultrasonic-assistedwild blueberry flavonoids

Identifiers

PMID41097500
PMCPMC12524316

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.