Evidence map›Paper›PMID 41097417›Full record

ArticleMolecules (Basel, Switzerland)2025

Identification of Selective α-Glucosidase Inhibitors via Virtual Screening with Machine Learning.

Fengyu Guo, Jiali Shi, Wenhua Jin, Feng Zhang, Hao Chen, Weibo Zhang, Yan Zhang, Chen Chong, Fazheng Ren, Pengjie Wang and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fengyu GuoDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Jiali ShiDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Wenhua JinDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Feng ZhangNational Technology Innovation Center for Dairy, Huhehaote 010000, China.
Hao ChenSuzhou Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Suzhou 215123, China.
Weibo ZhangDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Yan ZhangCollege of Food Science and Engineering, Gansu Agricultural University, Lanzhou 730070, China.
Chen ChongDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Fazheng RenDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.
Pengjie WangDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.ORCID 0000-0001-9975-6737
Ping LiuDepartment of Nutrition and Health, China Agricultural University, Beijing 100083, China.ORCID 0009-0008-2025-9331

Funding

National Technology Innovation Center for Dairy No 2023-KFKT-18
6 · The paper itself

Abstract

Given the limitations of clinical and potent natural α-glucosidase inhibitors, novel selective inhibitors are urgently needed. To accelerate discovery, we employed machine learning-integrated virtual screening to rapidly evaluate a library of 100 K

Indexed as

alpha-GlucosidasesGlycoside Hydrolase InhibitorsMachine LearningCatalytic DomainDrug Evaluation, PreclinicalHumansHydrogen BondingKineticsMolecular Docking SimulationProtein Bindingalpha-GlucosidasesGlycoside Hydrolase Inhibitorsmachine learningvirtual screeningα-glucosidase selective inhibitors

Identifiers

PMID41097417
PMCPMC12525602

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.