Evidence map›Paper›PMID 41097376›Full record

ReviewMolecules (Basel, Switzerland)2025

Advances in the Total Synthesis of Angular Triquinane-Type Natural Products.

Xin Wang, Dunfeng Liu, Yunfei Cheng

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xin WangSchool of Chemistry and Chemical Engineering, Huangshan University, Huangshan 245061, China.
Dunfeng LiuSchool of Chemistry and Chemical Engineering, Huangshan University, Huangshan 245061, China.
Yunfei ChengSchool of Chemistry and Chemical Engineering, Huangshan University, Huangshan 245061, China.

Funding

Huangshan University 2023xkjq008
6 · The paper itself

Abstract

This review provides a comprehensive summary of advances in synthetic strategies for structurally complex angular triquinane natural products, with a particular emphasis on terpenoids and alkaloids over the past two decades. The formidable challenge inherent in these frameworks lies in the stereoselective construction of the congested, angularly fused triquinane core bearing one or more quaternary stereocenters. We systematically categorize and critically evaluate the key methodologies employed to construct this central motif, highlighting four major strategic approaches: (i) The Pauson-Khand reaction; (ii) tandem or cascade cyclization processes; (iii) skeletal reorganization strategies; and (iv) other innovative methods, including ring-expansion, radical cyclizations, and photochemical pathways.

Indexed as

angular triquinanePauson–Khand reactionskeletal reorganizationtandem cyclization

Identifiers

PMID41097376
PMCPMC12525579

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.