Evidence map›Paper›PMID 41097284›Full record

ReviewMolecules (Basel, Switzerland)2025

The Versatility of NADES Across Applications.

David S Freitas, Artur Ribeiro, Artur Cavaco-Paulo, Carla Silva

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David S FreitasCentre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-6733-8928
Artur RibeiroCentre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-3298-5564
Artur Cavaco-PauloCentre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-7204-2064
Carla SilvaCentre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-6252-8693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural deep eutectic solvents (NADES) are produced by combining natural compounds, such as sugars, amino acids, or organic acids, to form a liquid at room temperature. Compared to other solvents, NADES own several strengths, including cost-effectiveness, ease of preparation, tunable properties, biorenewability, and biodegradability, making them suitable for a wide range of industrial sectors. Research on NADES requires careful consideration of their composition and physicochemical properties, as these can significantly influence their range of applications. In this context, the main objective of this review is to provide insights into the application of NADES in different areas that go from enzymatic processes and extraction of bioactives to the formulation of pharmaceutical and cosmetic products. This review includes several case studies on the use of enzyme-NADES systems (lipase and laccase) to synthesize new materials and on the extraction of bioactives with NADES, highlighting their direct application in cosmetics and pharmaceutical formulations.

Indexed as

deep eutectic solventsenzymatic processesextractionPharma-cosmeticssustainable solvents

Identifiers

PMID41097284
PMCPMC12525562

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.