Evidence map›Paper›PMID 41097253›Full record

ArticleNutrients2025

Lactoferrin and Osteopontin Cooperatively Promote Intestinal Epithelial Maturation in Neonatal Mice by Activating the Brg1/Notch1/Hes1 Pathway.

Wen Zhang, Chuangang Li, Ran Bi, Yao Lu, Yiran Zhang, Chenhong Shi, Ziyu Qiao, Yanan Sun, Juan Chen, Pengjie Wang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wen ZhangKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Chuangang LiCollege of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Ran BiKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Yao LuCollege of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China.ORCID 0000-0002-8426-477X
Yiran ZhangKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Chenhong ShiKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Ziyu QiaoKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Yanan SunKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Juan ChenKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Pengjie WangKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-9975-6737
Ran WangKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Fazheng RenKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.
Yixuan LiKKey Laboratory of Functional Dairy, Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100193, China.

Funding

National Natural Science Foundation of China No. 32401992
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA HelicasesIntestinal MucosaLactoferrinNuclear ProteinsOsteopontinReceptor, Notch1Transcription Factor HES-1Transcription FactorsAnimalsAnimals, NewbornCell DifferentiationFemaleMaleMiceMice, Inbred C57BLSignal TransductionDNA HelicasesHes1 protein, mouseLactoferrinNotch1 protein, mouseNuclear ProteinsOsteopontinReceptor, Notch1Smarca4 protein, mouseSpp1 protein, mouseTranscription Factor HES-1Transcription Factorsintestinal epitheliumlactoferrinneonatal miceNotch pathwayosteopontin

Identifiers

PMID41097253
PMCPMC12525966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.