Evidence map›Paper›PMID 41097223›Full record

ReviewNutrients2025

Adulteration of Sports Supplements with Anabolic Steroids-From Innocent Athlete to Vicious Cheater.

Daniela Puscasiu, Corina Flangea, Daliborca Vlad, Roxana Popescu, Cristian Sebastian Vlad, Sorin Barac, Andreea Luciana Rata, Cristina Marina, Ionut Marcel Cobec, Sorina Maria Denisa Laitin

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniela PuscasiuDepartment of Cell and Molecular Biology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.
Corina FlangeaDepartment of Biochemistry and Pharmacology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.
Daliborca VladDepartment of Biochemistry and Pharmacology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.
Roxana PopescuDepartment of Cell and Molecular Biology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-9387-1141
Cristian Sebastian VladDepartment of Biochemistry and Pharmacology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.
Sorin BaracSurgical Emergencies Department, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.
Andreea Luciana RataSurgical Emergencies Department, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0003-4009-2248
Cristina MarinaDepartment of Biochemistry and Pharmacology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.
Ionut Marcel CobecDepartment of Obstetrics and Gynecology, Faculty of Medicine, Medical Center-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-3240-4793
Sorina Maria Denisa LaitinDepartment of Infectious Diseases, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy, 2nd Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0009-0001-5436-5158

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some protein food supplements intended for athletes may be adulterated with pharmacologically active substances, including anabolic steroids and prohormones. The addition of these substances is aimed at enabling manufacturers to achieve rapid sales growth by promising quick increases in strength and muscle mass. However, the consumption of these products will lead to a positive result in a routine anti-doping test, along with all of the consequences that will directly affect an athlete's career and reputation. At the same time, the illicit use of anabolic steroids continues to evolve across numerous sport disciplines. Moreover, vicious cheaters try to cover up their illegal actions by using various pharmacological agents to mask detection in anti-doping tests. This narrative review focuses on two situations-the innocent athlete and the vicious cheater. The athlete involved in inadvertent doping will suffer the consequences of doping, making close collaboration with medical staff extremely important. The analytic strategies described here address anabolic steroid doping detection and cheating using masking agents. This approach, based on biochemical changes, examines how these substances interfere with the testosterone pathway, from synthesis to elimination. Using masking agents alters the steroid profile, and the modifications produced by each agent are the subject of a detailed presentation. For most honest athletes, these findings support the initiation, development, and refinement of strategies for identifying food supplements with added illegal substances. Every athlete must have access to these approaches in order to avoid becoming vulnerable to sports fraud.

Indexed as

Anabolic AgentsAthletesDietary SupplementsDoping in SportsDrug ContaminationFood ContaminationSubstance Abuse DetectionTestosterone CongenersAnabolic Androgenic SteroidsHumansAnabolic AgentsAnabolic Androgenic SteroidsTestosterone Congenersdietary supplement adulterationdopingidentification methodsillicit use in sportmasking agentstestosterone-derivative compounds

Identifiers

PMID41097223
PMCPMC12526240

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.