Evidence map›Paper›PMID 41097056›Full record

ArticleInternational journal of molecular sciences2025

NRDE2 Interacts with an Early Transcription Elongation Complex and Widely Impacts Gene Expression.

Marina Srbic, Chaïmaa Belhaouari, Raoul Raffel, Laurine Lemaire, Jerome Barbier, Julie Bossuyt, Charbel Akkawi, Xavier Contreras, Rosemary Kiernan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marina SrbicInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.
Chaïmaa BelhaouariInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.
Raoul RaffelGen2I, 31000 Toulouse, France.
Laurine LemaireInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.
Jerome BarbierInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.
Julie BossuytInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.
Charbel AkkawiInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.ORCID 0000-0002-8773-5127
Xavier ContrerasInstitut de Génétique Humaine, Univ Montpellier, CNRS, INSERM, 34396 Montpellier, France.ORCID 0000-0003-0748-6923
Rosemary KiernanInstitut de Génétique Humaine, Univ Montpellier, CNRS, 34396 Montpellier, France.ORCID 0000-0001-6645-0686

Funding

Agence Nationale de la Recherche HelicoAgence Nationale de Recherches sur le Sida et les Hépatites Virales 2021European Research Council RNAmedTGSMSD Avenir EpiMUM-3DSidaction 2021
6 · The paper itself

Abstract

NRDE2 is a highly conserved protein implicated in post-transcriptional gene silencing in

Indexed as

Gene Expression RegulationTranscription Elongation, GeneticHEK293 CellsHeLa CellsHumansIntronsProtein BindingProteomicsRNA HelicasesRNA Polymerase IIRNA SplicingRNA Splicing FactorsTranscription FactorsMTREX protein, humanRNA HelicasesRNA Polymerase IIRNA Splicing FactorsTranscription Factorsintron retentionNRDE2splicingtranscription

Identifiers

PMID41097056
PMCPMC12524662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.