Evidence map›Paper›PMID 41097051›Full record

ArticleInternational journal of molecular sciences2025

Lychee Seed Extract Targets Proliferation, Differentiation, and Cell Cycle Proteins to Suppress Human Colorectal Tumor Growth in Xenograft Models.

Szu-Nian Yang, Yi-Ping Chang, Oscar C Y Yang, Chi-Sheng Wu, Chiu-Chen Huang, Jia-Feng Chang, Chia-Ming Liang, Shun-Tai Dai, Lung Chen, Chih-Ping Hsu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Szu-Nian YangDepartment of Psychiatry, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330023, Taiwan.ORCID 0000-0002-6091-0263
Yi-Ping ChangDivision of Nephrology, Department of Internal Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330023, Taiwan.
Oscar C Y YangDivision of Hematology and Oncology, Department of Internal Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330023, Taiwan.
Chi-Sheng WuRenal Care Research and Health Promotion Association, New Taipei City 220050, Taiwan.
Chiu-Chen HuangDepartment of Post-Baccalaureate Veterinary Medicine, Asia University, Taichung 413305, Taiwan.
Jia-Feng ChangDivision of Nephrology, Department of Internal Medicine, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330023, Taiwan.ORCID 0000-0002-9903-7473
Chia-Ming LiangDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taoyuan Branch, Taoyuan 330023, Taiwan.
Shun-Tai DaiDepartment of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu 300150, Taiwan.
Lung ChenDepartment of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu 300150, Taiwan.
Chih-Ping HsuDepartment of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu 300150, Taiwan.

Funding

Taoyuan Branch of Taipei Veterans General Hospital TVGH-11401
6 · The paper itself

Abstract

Colorectal cancer (CRC) remains a leading global health challenge, and natural products are increasingly explored for their multi-targeted therapeutic potential.

Indexed as

Antineoplastic Agents, PhytogenicCell Cycle ProteinsCell DifferentiationColorectal NeoplasmsPlant ExtractsSeedsAnimalsApoptosisCell Line, TumorCell ProliferationHT29 CellsHumansMiceMice, NudeXenograft Model Antitumor AssaysAntineoplastic Agents, PhytogenicCell Cycle ProteinsPlant Extractschemopreventioncolorectal cancerEGFRKi-67lychee seed extractp21p53xenograft model

Identifiers

PMID41097051
PMCPMC12524773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.