Evidence map›Paper›PMID 41097038›Full record

ArticleInternational journal of molecular sciences2025

SPAchips: Microparticles Used for the Selective In Vitro Labelling of Microglia.

Justyna Gargas, Justyna Janowska, Beata Dabrowska-Bouta, Marta Sidoryk-Wegrzynowicz, Alberto M Hernández-Pinto, Rubén Miguez, Teresa Suárez, Lidia Struzynska, Joanna Sypecka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Justyna GargasNeuroRepair Department, Mossakowski Medical Research Institute Polish Academy of Sciences, 5 Pawinskiego Str, 02-106 Warsaw, Poland.ORCID 0000-0002-4491-7633
Justyna JanowskaNeuroRepair Department, Mossakowski Medical Research Institute Polish Academy of Sciences, 5 Pawinskiego Str, 02-106 Warsaw, Poland.ORCID 0000-0003-0093-8173
Beata Dabrowska-BoutaLaboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawinskiego Str, 02-106 Warsaw, Poland.
Marta Sidoryk-WegrzynowiczLaboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawinskiego Str, 02-106 Warsaw, Poland.ORCID 0000-0003-3916-7660
Alberto M Hernández-Pinto4cell Nanodevices SL. CAIT-UPM Campus de Montegancedo s/n, Pozuelo de Alarcón, 28223 Madrid, Spain.ORCID 0000-0001-6658-5054
Rubén Miguez4cell Nanodevices SL. CAIT-UPM Campus de Montegancedo s/n, Pozuelo de Alarcón, 28223 Madrid, Spain.
Teresa SuárezCentro de Investigaciones Biológicas Margarita Salas (CIBMS-CSIC), C/Ramiro de Maeztu 9, 28040 Madrid, Spain.ORCID 0000-0002-4553-3818
Lidia StruzynskaLaboratory of Pathoneurochemistry, Department of Neurochemistry, Mossakowski Medical Research Institute, Polish Academy of Sciences, 5 Pawinskiego Str, 02-106 Warsaw, Poland.
Joanna SypeckaNeuroRepair Department, Mossakowski Medical Research Institute Polish Academy of Sciences, 5 Pawinskiego Str, 02-106 Warsaw, Poland.

Funding

Mossakowski Medical Research Institute Polish Academy of Sciences Statutory Fund no 6/2025
6 · The paper itself

Abstract

Both basic and preclinical research, as well as the development of new therapies, require tools that allow for the selective labelling of specific cell types and the targeted delivery of drugs. The developed tools must then be validated in biological systems. In view of the lack of effective therapies for many neurodevelopmental disorders, including neonatal brain injuries, we decided to use the newly described, innovative SPAchips

Indexed as

MicrogliaStaining and LabelingAnimalsAnimals, NewbornAstrocytesCells, CulturedCerebral CortexFluorescent Antibody TechniqueMiceMice, Inbred C57BLMicroscopy, ConfocalNeuronsOligodendrogliaPrimary Cell CultureRatsRats, Wistarastrocytesmicroglianeuronsoligodendrocytesrat primary culturesSPAchips®

Identifiers

PMID41097038
PMCPMC12525483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.