Evidence map›Paper›PMID 41096975›Full record

ReviewInternational journal of molecular sciences2025

Fusobacterium Nucleatum in Colorectal Cancer: Relationship Among Immune Modulation, Potential Biomarkers and Therapeutic Implications.

Dalila Incognito, Giuliana Ciappina, Claudia Gelsomino, Antonio Picone, Pierluigi Consolo, Alessandra Scano, Tindara Franchina, Nicola Maurea, Vincenzo Quagliariello, Salvatore Berretta and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Fusobacterium nucleatum, succinate signaling, and immunotherapy resistance in colorectal cancer: clinical relevance and translational opportunities.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  4. Medicina (Kaunas, Lithuania) · 2026
    Article
  5. Review
  6. Article
  7. Pathogenic Roles ofPathogens (Basel, Switzerland) · 2026
    Review
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  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dalila IncognitoMedical Oncology Unit, Department of Human Pathology "G. Barresi", School of Specialization in Medical Oncology, University of Messina, 98122 Messina, Italy.
Giuliana CiappinaSection of Experimental Medicine, Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-0813-3126
Claudia GelsominoMedical Oncology Unit, Department of Human Pathology "G. Barresi", School of Specialization in Medical Oncology, University of Messina, 98122 Messina, Italy.
Antonio PiconeDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.ORCID 0009-0006-0924-2163
Pierluigi ConsoloUnit of Digestive Endoscopy, G. Martino University Hospital, University of Messina, 98125 Messina, Italy.
Alessandra ScanoDepartment of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.
Tindara FranchinaDepartment of Human Pathology of Adulthood and Childhood "G. Barresi", University of Messina, 98122 Messina, Italy.
Nicola MaureaDivision of Cardiology, IRCCS Istituto Nazionale Tumori "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0003-3704-0092
Vincenzo QuagliarielloDivision of Cardiology, IRCCS Istituto Nazionale Tumori "Fondazione G. Pascale", 80131 Naples, Italy.ORCID 0000-0002-4557-5401
Salvatore BerrettaDepartment of Human Pathology "G. Barresi", G. Martino University Hospital, University of Messina, 98122 Messina, Italy.
Alessandro OttaianoIstituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via M. Semmola, 80131 Naples, Italy.ORCID 0000-0002-2901-3855
Massimiliano BerrettaDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-9837-9148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorColorectal NeoplasmsFusobacterium InfectionsFusobacterium nucleatumAnimalsEpithelial-Mesenchymal TransitionHumansTumor MicroenvironmentBiomarkers, Tumorbiomarkerscolorectal neoplasmdrug resistanceFusobacterium nucleatumimmune checkpoint inhibitorsimmunotherapy

Identifiers

PMID41096975
PMCPMC12525060

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.