Evidence map›Paper›PMID 41096953›Full record

ArticleInternational journal of molecular sciences2025

Elevated Serum Levels of miRNA-155 in Children with Atopic Dermatitis: A Potential Biomarker of Disease.

Natalia Gołuchowska, Aldona Ząber, Sylwia Walczewska, Agata Będzichowska, Klaudia Brodaczewska, Aleksandra Majewska, Bolesław Kalicki, Agata Tomaszewska

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natalia GołuchowskaDepartment of Pediatrics, Nephrology and Allergology, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0000-0002-1928-175X
Aldona ZąberDepartment of Pediatrics, Nephrology and Allergology, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0009-0004-3577-3203
Sylwia WalczewskaDepartment of Pediatrics, Nephrology and Allergology, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0009-0003-8052-2852
Agata BędzichowskaDepartment of Pediatrics, Nephrology and Allergology, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0000-0002-1756-7316
Klaudia BrodaczewskaLaboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0000-0003-2374-3600
Aleksandra MajewskaLaboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0000-0003-1271-4679
Bolesław KalickiDepartment of Pediatrics, Nephrology and Allergology, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0000-0003-1606-5100
Agata TomaszewskaDepartment of Pediatrics, Nephrology and Allergology, Military Institute of Medicine-National Research Institute, Szaserów 128, 04-141 Warsaw, Poland.ORCID 0000-0003-3255-7623

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is the most common inflammatory skin disease in the pediatric population. In recent years, the role of microRNAs in inflammatory and immunological mechanisms as specific biomarkers of AD has received growing attention. The aim of the present study was a quantitative assessment of serum expression levels of miR-100, miR-224 and miR-155 in children with AD compared with healthy peers, and an analysis of their potential associations with clinical disease phenotype, severity of skin lesions (SCORAD), cytokine profile, immunological parameters and the presence of concomitant allergic diseases. The study included 12 children with AD and 9 healthy children. Selected miRNAs were isolated from serum, followed by reverse transcription using universal primers and quantification by qRT-PCR. Children with AD exhibited significantly higher expression levels of miR-155 compared with controls (

Indexed as

BiomarkersDermatitis, AtopicMicroRNAsCase-Control StudiesChildChild, PreschoolEosinophilsFemaleHumansMaleBiomarkersMicroRNAsMIRN155 microRNA, humanatopic dermatitisbiomarkerseczemainflammationmiRNA-100miRNA-155miRNA-224

Identifiers

PMID41096953
PMCPMC12525480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.