Evidence map›Paper›PMID 41096948›Full record

ArticleInternational journal of molecular sciences2025

Glia Cells Are Selectively Sensitive to Nanosized Titanium Dioxide Mineral Forms.

Eszter Geiszelhardt, Erika Tóth, Károly Bóka, Norbert Bencsik, Katalin Schlett, Krisztián Tárnok

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eszter GeiszelhardtDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, H-1117 Budapest, Hungary.
Erika TóthDepartment of Microbiology, Institute of Biology, Eötvös Loránd University, H-1117 Budapest, Hungary.
Károly BókaDepartment of Plant Anatomy, Institute of Biology, Eötvös Loránd University, H-1117 Budapest, Hungary.
Norbert BencsikDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, H-1117 Budapest, Hungary.ORCID 0000-0001-9553-3851
Katalin SchlettDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, H-1117 Budapest, Hungary.ORCID 0000-0001-9265-4236
Krisztián TárnokDepartment of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, H-1117 Budapest, Hungary.ORCID 0000-0003-3491-4014

Funding

National Research, Development and Innovation Office, Hungary PD137855National Research, Development and Innovation Office, Hungary Thematic Excellence Programme (TKP2020-IKA-05)University Excellence Fund of Eötvös Loránd University, Budapest, Hungary 2024-11-14/176
6 · The paper itself

Abstract

Nanosized titanium dioxide is widely used by the industry, e.g., in pigments, suncreams, and food colors. Its environmental and biological effects have been investigated in the past; however, few studiesd have focused on its crystal structure-specific effects. In our experiments, the toxicity of two types of synthetic nanoparticles was examined on primary neural cultures with different cell compositions using MTT and LDH assays. Primary murine cell cultures containing only astroglia cells originated from two brain regions, as well as mixed neurons and glia cells or microglia cells exclusively, were treated with anatase (15.8 ± 1.7 nm average diameter) and rutile (46.7 ± 2.2 nm average length and 13.7 ± 0.7 nm average diameter) TiO

Indexed as

Metal NanoparticlesNanoparticlesNeurogliaTitaniumAnimalsAstrocytesCells, CulturedCell SurvivalMiceMicrogliaNeuronsTitaniumtitanium dioxidecell-type dependent sensitivitycrystal structurein vitro cell viabilitynanoparticlesneural cellstitanium dioxide

Identifiers

PMID41096948
PMCPMC12524891

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.